Energy Reactions In Cells Flashcards

1
Q

Define metabolism

A

Set of processes that derive energy and raw materials from food and use them for repair, growth and activity of tissues of the body to sustain life

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2
Q

How are metabolic pathways seperated?

A

Some in all cells
Some restricted to some cells
Some restricted to compartments

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3
Q

What are catabolic pathways?
How are they related to energy?
Oxidative or reductive?

A

Break down larger molecules into smaller ones
Release free energy
Oxidative

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4
Q

What are anabolic pathways?
How are they related to energy?
Oxidative or reductive?

A

Synthesise large components from intermediary metabolites
Use energy from catabolism
Reductive

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5
Q

What is gibs free energy?

A

Useful energy

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6
Q

Key point about exergonic reactions

A

Only reactions that occur spontaneously

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7
Q

If ATP is NOT a carrier what is it?
Why?

A

A store
Limited amount of ADP

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8
Q

Why is ATP energy release controlled?

A

Stable in the absence of specific catalysts

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9
Q

What is AMP?

A

Has one phosphate group

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10
Q

Components of ATP

A

Three phosphate groups
Ribose sugar
Adenine

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11
Q

Why is AMP important?

A

Increases ATP production by glycolysis

Activates ATP dependent kinase that regulates gene expression

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12
Q

What is the enzyme that catalyses 2ADP > ATP + AMP

A

Adenylate kinase

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13
Q

What is creatine phosphate?

A

The main high-energy, phosphate-storage molecule of muscle

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14
Q

Give a reaction including creatine and ATP
Give the catalyst

A

Creatine + ATP > Creatine Phosphate + ADP
Creatine kinase - catalyst

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15
Q

How does a creatine phosphate work?

A

[ATP] high, leads to creatine phosphate formation
[ATP] low, leads to ATP formation

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16
Q

What does a cytosolic enzyme mean?

A

Appears in blood after cell damage

17
Q

What is creatine kinase formed from?

A

Two subunits - M and B
Can be MM, BB or MB

18
Q

How is creatinine produced?

A

Breakdown product of creatine and creatine phosphate

Spontaneous reaction at a constant rate

19
Q

What does creatinine show (3)?

A
  • kidney function (excreted via kidneys)
  • excretion per 24hours is proportional to muscle mass - measure of muscle mass
  • urine dilution
20
Q

What type of food has the most energy?

A

Fats

21
Q

What is energy measured in?

A

KiloJoules

22
Q

Order carbohydrates, fats and proteins in the amount of energy

A

Fats
Carbohydrates
Proteins

23
Q

What is the main form of energy in cells?

A

Chemical bonds

24
Q

Where is creatine broken down?
Into what?

A

Kidneys
Creatinine

25
Q

What stimulates more ATP production?
Give an example of a catabolic process to make ATP

A

When ATP conc decreases

2ADP>ATP+AMP (adenylate kinase)

26
Q

Which phosphate group is hydrolysed in ATP?

A

Gamma phosphate (y)

27
Q

Which molecule can be used to replenish ATP from ADP?

A

Phosphocreatine