Energy Metabolism Flashcards

1
Q

what is the cellular source of energy

A

ATP

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2
Q

what does ATP do/ where does it come from? `

A
  • sustains physical energy, anabolism, active transport

- supplied by the macronutrients in the diet

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3
Q

how many chemistry calories are in a food calorie

A

1000 chemistry calories = 1 food calorie

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4
Q

how many KJs are in 1 food calorie

A

1 food calorie = 4.18 KJ

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5
Q

describe positive energy balance

A
  • weight gain/ obesity
  • infertility
  • increased blood lipids
  • insulin resistance
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6
Q

describe negative energy balance

A

weight loss

  • infection
  • loss of performance
  • reduced bone mass
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7
Q

what did Antoine Lavoisier do?

A
  • compared heat produced by a genie pot with the production of co2
  • ice calorimeter (heat produced estimated by the amount of ice that melts
  • CO2 formed from the reaction between oxygen and organic matter
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8
Q

what did Justin Liebig recognize?

A

Justin Leigib recognized that protein, carbohydrates, and fats are oxidized by the body

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9
Q

what did max rubner do?

A

max rubner measured energy values of certain foods to determine caloric content

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10
Q

what is calorimetry

A

it is the measurement of heat production

- uses heat as an indicator of the amount of energy stored in the chemical bonds of food

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11
Q

what are the steps when carrying out bomb calorimetry

A
  1. dry and weight sample and place in enclosed chamber- with oxygen
  2. ignite the sample
  3. heat released is absorbed by the water and measured
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12
Q

what are the potential sources of error in terms of bomb calorimetry

A
  • overestimate energy (we dont digest like a bomb calorimeter)
  • doesn’t take into account energy needed for digestion/ absorption
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13
Q

what is the Atwater value for CHO

A

4 kcal/g

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14
Q

what is the Atwater value for fat

A

9 kcal/g

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15
Q

what is the Atwater value for protein

A

4kcal/g

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16
Q

what are Atwater values

A

physiological fuel values

- take into account incomplete digestion

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17
Q

why does fat provide more kcal per gram vs CHO or protein

A

the chemical structure of CHO, fat, and protein indfluence the heat combustion for macronutrients

18
Q

describe the chemical structure of CHO

A

ratio of hydrogen to oxygen= 2:1

19
Q

describe the chemical structure of protein

A
  • has nitrogen, which contributes to gross energy

however, our bodies dont use nitrogen for energy

20
Q

describe the chemical structure of lipids

A
  • less oxidized than CHO and protein
  • ratio of hydrogen to oxygen I much greater than 2:1
  • lipids have lots of hydrogen atoms available for cleavage and oxidation for energy
21
Q

what does the bomb calorimeter measure

A

the bomb calorimeter measures gross energy of a compound

22
Q

what are the factors that affect heat combustion of fatty acids

A
  • unsaturation (the more double bonds, the less energy provided by that molecule)
  • chain length (the longer the chain, the more energy provided)
23
Q

what is the heat increment of feeding (HIF)

A
  • thermic effect of food
  • energy used for digestion, absorption, distribution, and storage of nutrients
  • is about 5-30% of daily energy usage
  • used to determine net energy
24
Q

what is net energy

A

net energy= metabolized energy - HIF

- supports basal metabolism, physical activity, growth, pregnancy, etc

25
Q

how much energy is partitioned towards HIF

A

5-30% of the metabolized energy is used for basic digestion mechanisms

26
Q

what are the 4 primary components to energy expenditure?

A
  1. basal metabolic rate (BMR)
  2. Thermic effect of food (HIF)
  3. physical activity energy expenditure (PAEE)
  4. thermoregulation (a minor contribution)
27
Q

what tissued are most reflective of the BMR

A

muscle and bone

28
Q

what is the equation used when calculating BMR

A

BMR= A * [M^0.75] kcal/day

  • A= metabolically active tissue (for humans, A=70)
  • M = body weight in Kg
29
Q

what is kleibers law

A

(0. 75)

- a constant used for all vertebrates, invertebrates, and unicellular organisms when calculating BMR

30
Q

what are the factors that can affect BMR

A
  • genetics
  • age
  • sex
  • tissue proportions
  • temperature
31
Q

how does genetics affect BMR

A

inheritance of a fast or slow metabolic rate

32
Q

how does exercise affect BMR

A

exercise changes body tissue proportions

muscle uses more energy than fat

33
Q

what does indirect calorimetry measure?

A

O2 intake, CO2 output

- energy- releasing reactions in the body depends on the use of oxygen

34
Q

what does direct calorimetry measure?

A

Heat output

- measures the heat a person generates (total heat loss)

35
Q

what is the issue with indirect calorimetry?

A

this method can not account for anaerobic processed (ie- production of lactic acid)

  • hyperventilation
  • masks are impractical
36
Q

what is the issue with direct calorimetry

A
  • expensive

- impractical

37
Q

compare direct vs indirect calorimetry

A

<1% difference

very comparable

38
Q

what is the respiratory quotient (RQ)

A

a ratio of metabolic gas exchange
provides information about:
- energy expenditure
- biological substrate being oxidized

39
Q

what is the equation used when calculating RQ (respiratory quotient)

A

RQ= (CO2 produced)/(O2 consumed)

40
Q

why do RQ values for macronutrients vary

A

differentiations in chemical composition mean that each macronutrient required a different amount of oxygen intake in relation to CO2 produced

ie- fats require almost three times as much oxygen (in comparison to carbs) to complete the digestion