Energy Flashcards
Measure energy expenditure: Direct Calorimetry?
Calorimeter
Measure energy expenditure: Indirect Calorimetry?
Open-circuit Spirometry—>
Portable systems Douglas bag Computerised (breath-breath)
Measure energy expenditure: Stable Isotopes?
2H+18O—>
Doubly labelled water (2H2 18O)—>
Ingestion—>
Distribution (5h)—>
Excretion: Urine (2H+18O) + Breath( 18O)
Measure energy expenditure: Prediction Equations
Prediction equations
Components of energy expenditure?
- Basal Metabolic Rate
- Thermic Effect of Food
- Thermic Effect of Activity
- Growth (children, pregnancy)
Basal Metabolic Rate: A measure of an individual’s metabolism in a basal state?
– Immediately after waking (awake)
– Lying supine (eg resting),
– Fasted (all food digested/absorbed, eg >12h fast)
– Thermally neutral conditions
– (eg. no other physical or psychological stimulation).
Basal Metabolic Rate: Reflects energy required for:
– Breathing / circulation / ion pumps (eg normal bodily functions)
Basal Metabolic Rate: part 3?
- Requires specialist equipment to measure directly
- Several prediction equations
- BMR typically accounts for 40-70% energy expenditure.
Resting Metabolic Rate (RMR)?
- Failure to meet above conditions (eg arousal component)
* >BMR by ~10%
RMR in athletes: Background?
• Contribution of metabolic rate to total
EE varies depending on activity level.
RMR in athletes: Method?
- 10 female endurance runners v 10 sedentary controls.
* Thermic effect of meal (TEM) and thermic effect of activity (TEA).
RMR in athletes: Conclusion
• RMR accounted for 47% of energy expenditure in athletes compared to 61%
in sedentary controls.
Factors that influence BMR: Age?
- Declines by ~1-2% by year from 20 to 70yr
* Linked to muscle loss and brain weight
Factors that influence BMR: Gender?
- Menstrual cycle fluctuations (100 – 300kcal/d)
* Males > Females (body composition)
Factors that influence BMR: Body Size?
- Fat-free mass
* Muscle is very metabolically active
Factors that influence BMR: Exercise?
- Alterations in fat-free mass
- Muscle damage
- EPOC (intensity/duration dependent)
Factors that influence BMR: Nutritional Status?
• Undernutrition
Factors that influence BMR: Psychological factors?
• Anxiety can increase BMR
Factors that influence BMR: Hormonal factors?
• Hypothyroidism reduces BMR
Factors that influence BMR: Disease/Injury?
• Trauma, fever, injury increases BMR
Energy Availability: Methods?
- 8 males completed 4 x 9d exercise& diet interventions
* Ex = 3 x 40min cycle/d
Energy Availability: Results?
• Energy Availability ~30kcal/kg FFM
Energy Availability: Conclusion?
• Energy balance decreased by 90kcal/d towards zero indicating the slowing of various metabolic processes. This leads to detrimental health affects.
Prediction Equation: Method?
- Harris-Benedict (1919)
- Cunningham (1980)
- Owen et al (1986, 1987)
- Mifflin et al (1990)
- WHO (1985)
Prediction Equation: Results?
• All prediction equations underestimated RMR except for the Cunningham equation (Why do you think this is?)
Prediction Equation: Critical Analysis?
- Recognise the limitations of these predictive equations
- Study population v New population
- Age, height, weight, FFM, gender
- Activity (Athletes v sedentary)
Components of energy expenditure?
- Basal Metabolic Rate
- Thermic Effect of Food
- Thermic Effect of Activity
- Growth (children, pregnancy)
Thermic Effect of Food?
- The increase in EE above RMR that occurs due to the ingestion of food
- Typically accounts for 6-10% of daily EE.
- Includes the energy required for:
- Digestion
- Absorption
- Transport
- Metabolism
- Storage
Thermic Effect of Food: Dietary Factors affecting TEF?
- Protein
- Carbohydrate
- Fat
Thermic Effect of food: Method?
- PLA meal vs 400kcal meal consisting of CHO, FAT, PRO
* Metabolic Rate - Indirect calorimetry (90min)
Thermic Effect of food: Results?
• All test meals increased metabolic rate with the greatest seen in protein, then carbohydrate and then fat.
Thermic Effect of food: Discussion?
• This is a result of the lower energy requirement to store fat as TG, than proteins (synthesis of new AA) and carbohydrate (storage as glycogen)
Thermic effect of activity: Physical activity ratio?
• Energy cost of activity : BMR
Thermic effect of activity: Physical Activity Level?
- Daily total energy expenditure : BMR
* Old method (summed PAR, SPA?)
Thermic effect of activity: Metabolic Equivalents (MET’s)?
• Work metabolic rate : RMR
• A fixed rate of oxygen consumption assumed to represent that of an adult
measured during supine rest
• 1 MET is equivalent to 3.5ml/kg/min (~1kcal/kg/h)
PAL Matrix for EAR: Assumptions in EAR?
- Basal Metabolic Rate
* Schofield et al (1985) Equation
PAL Matrix for EAR: Physical Activity Level?
• Sleeping
– 8h/24hr
• Occupation
– (7.5h/24h for 5d = 5.5h/7d)
• Non-occupational (10.5h) – 8.5h x 1.4PAR plus: – Non-active – 2h at 2PAR – Mod active – 2h at 3PAR – Very active – 2h at 4PAR
Establishing the EAR?
• An EAR is reported for energy, not the RNI as the RNI would represent an excess energy intake for most of the population. Due to a skewed distribution (sedentary) the median, not mean, is used.
Establishing the EAR: Calculations?
• Derived from doubly labelled water and basal metabolic rate (Henry 2005)
• PAL - 1.49 (25th centile)
– Less active(immobile)
• PAL = 1.63
– Average activity
• PAL = 1.78 (75th centile)
– More active
– (eg those trying to increase activity levels)
Establishing the EAR: Considerations - Physical Activity Level?
- +0.15PAL - 30min moderate intensity exercise ≥5d/wk
- +0.20PAL – 60min brisk walking (4-5mph, daily)
- +0.30PAL - 60min active sport 5times/wk
- +0.40PAL – 60min jogging (6mph, daily)
- +0.60 PAL - 60min of intense aerobic sport 5 times/wk
Current Energy Intake & DRV in the UK: Considerations for DRV?
• A level to maintain a healthy body mass
in healthy people at their existing levels
of physical activity.
• Recognises overweight/obesity
prevalence
Current Energy Intake & DRV in the UK: Current UK Intake?
- Men = 8.88 ± 2.58MJ/d (~2111kcal/d)
* Women = 6.78 ± 1.91MJ/d (~1613kcal/d)
Metabolisable energy?
Gross Energy: unabsorbed—->
Digestible energy: Incomplete catabolism’s—>
Metabolisable energy
Protein: 5.65kcal/g—>
92%—>
4kcal/g
Fat: 9.40kcal/g—>
95%—>
9kcal/g
Carbohydrates: 4.10kcal/g—>
97%—>
4kcal/g
Dietary energy sources: Conversion factors?
- 1 kcal = 4.184kJ
* 1kJ = 0.239kcal
Dietary energy sources: Macronutrients?
- Protein – 4kcal/g
- Carbohydrate – 4kcal/g
- Fat – 9kcal/g
- Alcohol – 7kcal/g