Endometrial cancer Flashcards

1
Q

Most common type of endometrial cancer

A

adenocarcinoma

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2
Q

Adenocarcinoma of the endometrium is an … dependent cancer

A

oestrogen

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3
Q

any woman presenting with postmenopausal bleeding has … until proven otherwise

A

endometrial cancer

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4
Q

key risk factors for endometrial cancer (2)

A

obesity
diabetes

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5
Q

what percentage of endometrial hyperplasia goes on to be cancerous

A

less than 5%

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6
Q

How can endometrial hyperplasia be treated

A

IUS
continuous oral progestogens

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7
Q

… menstruation increases the risk of endometrial cancer

A

early onset

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8
Q

… menopause increases the risk of endometrial cancer

A

late

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9
Q

… HRT increases the risk of endometrial cancer

A

oestrogen only

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10
Q

… pregnancies increases the risk of endometrial cancer

A

no / fewer

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11
Q

what gynae condition increases the risk of endometrial cancer

A

PCOS

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12
Q

what breast cancer medication increases the risk of endometrial cancer

A

tamoxifen

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13
Q

for endometrial protection women with PCOS should have one of (3)

A

COCP
IUS
cyclical progestogens

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14
Q

NICE recommends referral for a transvaginal ultrasound to rule out endometrial cancer in women over 55 years with: (2)

A

unexplained vaginal discharge
visible haematuria with either raised platelets, anaemia or raised glucose

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15
Q

investigations to remember for diagnosing and excluding endometrial cancer: (3)

A

transvaginal USS
pipelle biopsy
hysteroscopy and endometrial biopsy

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16
Q

FIGO stage 1 endometrial cancer

A

confined to uterus

17
Q

FIGO stage 2 endometrial cancer

A

invades cervix

18
Q

FIGO stage 3 endometrial cancer

A

invades ovaries, fallopian tubes, vagina or lymph nodes

19
Q

FIGO stage 4 endometrial cancer

A

invades bladder, rectum or beyond the pelvis

20
Q

The usual treatment for stage 1 and 2 endometrial cancer

A

total abdominal hysterectomy with bilateral salpingo-oophorectomy

21
Q

what hormone can be used to slow the progression of endometrial cancer

A

progesterone