Endocrinopathies

Question 1

ADH

Underlying cancer: small cell carcinoma of the lung

Answer 1

SIADH

Question 2

Parathyroid hormone-related protein (PTHrp)

Underlying cancer:

• Squamous cell carcinoma of the lung
• breast ca
• renal ca

Answer 2

Hypercalcemia

Question 3

Insulin or insulin-like substance

Underlying cancer: ovarian ca, fibrosarcoma

Answer 3

Hypoglycemia

Question 4

Serotonin, bradykinin

Underlying cancer:

• hepatocellular ca
• bronchial adenoma (carcinoid)
• pancreatic carcinoma

Answer 4

Carcinoid syndrome

Question 5

Erythropoietin

Underlying cancer:

• gastric and renal ca
• cerebellar hemangioma

Answer 5

Polycythemia

Question 6

Antibodies to presynaptic Ca channel

Underlying cancer: lung ca

Answer 6

Lambert-Eaton myasthenia

Question 7

EGF

Visceral malignancies

Answer 7

Acanthosis nigricans

Question 8

Lung ca

Answer 8

Hypertrophic osteoarthropathy (clubbing)

Question 9

Mucins

Underlying cancer: Pancreatic ca, lung ca

Answer 9

Trousseau syndrome

Question 10

Hypercoaguability

Underlying cancer: colon ca

Answer 10

Nonbacterial thrombotic endocarditis

Question 11

Thymoma

Answer 11

Red cell aplasia

Question 12

Immune complexes

Underlying cancer: Hodgkin’s lymphoma, lung ca

Answer 12

Nephrotic syndrome

Question 13

ACTH or ACTH-like substance

Underlying cancer:

• small cell carcinoma of lung
• pancreatic carcinkma
• neural tumors

Answer 13

Cushing syndrome