Endocrinology

Question 1

What can cause failure of the kidneys to respond to ADH?

Answer 1

1. hypercortisolaemia
2. e. coli toxin (pyo)
3. hypercalcaemia
4. hyperthyroidism (increased renal blood flow)
5. osmotic diuresis (glycosuria)
6. structural renal tubular damage

Question 2

What is the treatment of choice for central diapetes insipidous?

Answer 2

Conjunctival or subcutanous desmopressin acetate. Good prognosis.

Question 3

What do the parafollicular cells of the thyroid secrete?

Answer 3

Calcitonin - blood calcium regulation (reduction)

Question 4

Which hormone is not primrily controlled by the HPA?

Answer 4

Glucagon - responds to glucose levels in the blood

Question 5

A lack of mineralocorticoid (aldosterone) secretion would cause…

Answer 5

Hyponatreamia and hyperkalaemia

Question 6

The hormone with the greatest effect on basal metabolic rate is…

Answer 6

T3 (triiodothyronine)

Question 7

You see a 2yo, male, pomeranian with bilaterally symmetrical alopecia of the neck, trunk, pinnae and tail. Tests rule out the possibility of HyperA and HypoT… what other endocrinopathy could be affecting this dog?

Answer 7

Growth Hormone Responsive Dermatosis

Question 8

What disease might you suspect in any poorly controlled diabetic cat?

Answer 8

Feline Acromegaly (excessive GH secretion - diabetogenic)

Question 9

What is the effect of thyroid hormone on glucose/protein/fat metabolism?

Answer 9

Promotes glucose and fat utilisation but spares protein.