Endocrinology

Question 1

Catecholamines in urine, hypertension, headache and palpitations

Answer 1

Phaeochromocytoma

Question 2

Tanned skin without being on holiday

Answer 2

Addison’s disease

Question 3

Increased shoe size, ‘spade hands’, wedding ring too tight

Answer 3

Acromegaly

Question 4

Signs of hyperthyroidism plus any eye changes, gritty eyes, smooth velvety skin

Answer 4

Graves’ disease

Question 5

Moon face, proximal weakness, stretch marks, buffalo hump, abdominal fat

Answer 5

Cushing’s syndrome

Question 6

Ketones on breath (pear drop/sweet smell)

Answer 6

DKA

Question 7

Deep laboured breathing (Kussmual breathing)

Answer 7

Metabolic acidosis esp. DKA

Question 8

“Orphan Annie” nuclei

Answer 8

Papillary thyroid cancer

Question 9

Bone pain, stones, abdominal pain, psychiatric problems (bones, stones, groans, moans)

Answer 9

Hypercalcaemia (hyperparathyroidism)

Question 10

Psammoma bodies

Answer 10

Papillary thyroid cancer

Question 11

Butterfly rash

Answer 11

SLE

Question 12

Heat intolerance, palpitations

Answer 12

Hyperthyroidism

Question 13

Cold intolerance, weight gain

Answer 13

Hypothyroidism

Question 14

Anosmia and isolated GnRH deficiency

Answer 14

Kallmann’s syndrome

Question 15

Trousseau sign, Chvostek sign and QT prolongation on ECG

Answer 15

Hypocalcaemia

Question 16

Acute management of hypocalcaemia

Answer 16

IV calcium gluconate (10ml of 10% calcium gluconate over 10 minutes in 50% dextrose or saline)

Question 17

Brachydactyly of the 4th metacarpal

Answer 17

Pseudohypoparathyroidism