Endocrinology

Question 1

Hyperthyroidism LAB values

Answer 1

TSH < 0.1 mU/L
HI serum total free T4
HI T3 resin uptake

Question 2

Hypothyroidism LAB values

Answer 2

TSH > 5 mU/L
low serum total T4
low T-3 resin uptake

Question 2

BPH lab value

Answer 2

PSA > 4 prostate CA

Question 3

What are the causes for elevated ESR (sedimentation rate)?

Answer 3

• rheumatoid arthritis /RA
• Auto-immune disease, i.e., lupus
• temporal arteritis
• inflammation)

Question 4

What causes an elevated CRP: C reactive protein?

Answer 4

• inflammation
• autoimmune disease
• a risk for heart disease

Question 5

Characteristics of Graves or hyperthyroidism and s/sx

Answer 5

Onset age 20 - 40
Prevalent in females (8:1 females:males)

Low TSH
Hi T3 & T4

Physical findings: goiter, opthalmopathy

Question 6

Characteristics of subclinical hyperthyroidism

Answer 6

low TSH

NL unbound T4

Question 7

Characteristics of hypothyroidism

Answer 7

HI TSH

Question 8

Signs of adrenal insufficiency. aka Addison’s disease

Answer 8

early-morning cortisol < 5 mcg/dL
with INCREASED ACTH (2x above upper limit of normal)

Question 9

What is the test to dx Cushing’s dz?

Answer 9

Dexamethasone suppression test

occurs in patients with excess cortisol

Question 10

How does glyburide cause hypoglycemia?

Answer 10

A sulfonylurea that stimulates insulin secretion from the beta cells of the pancreas.

If given w/out adequate food intake will cause hypoglycemia