Endocrinology Flashcards
ADH function
Reabsorption of water by renal tubule
Vasoconstriction
Posterior pituitary hormones
Oxytocin
ADH
Anterior pituitary hormones
TSH FSH LH GH ACTH PRL
ACTH
Adrenal cortex to produce aldosterone and cortisol
Largest endocrine gland
Thyroid
Thyroid hormones
Thyroid follicular- T3/T4
Para follicular- Calcitonin
Thyroid follicular cells
Concentrate iodine
Peroxidase and diiodinase enzyme
T3/T4
Thyroglobulin
Cells of parathyroid gland
Chief- increase calcium level, calcitriol release, absorption of SI increased
Oxyphil
PTH
Stimulates Osteoclast formation
zona glomerulosa
Mineralocordicoids
Aldosterone
Regulates ratio of sodium and potassium
zona fasciculata
Glucocorticoids
Cortisol and corticosterone
Stimulate metabolism of lipids, proteins, glucose
Resist stress, repair tissues
zona reticularis
gonadocorticoids
androgens
Regulates salt, sugar, and sex
Islets of pancreas
Alpha cells secrete glucagon when blood glucose levels drop.
Beta cells secrete insulin when blood glucose levels are elevated.
Delta cells synthesize somatostatin, also described as growth hormone-inhibiting hormone,
F cells secrete pancreatic polypeptide to suppress and regulate somatostatin secretion from delta cells
pinealocytes secrete
melatonin (night ) and serotonin (day)
helps regulate a circadian rhythm (24-hour body clock)
affect the gonadotropin releasing hormone synthesis
thymopoietin and thymosins
T lymphocyte differentiation, growth and maturation
Kidney
Erythropoietin
Juxtaglomerula apparatus
Hyper secretion of thyroid
Graves disease High metabolism Sweating Nervousness Weight loss Rapid heart rate
Hypo secretion of thyroid
cretinism(Children) and Myxedema (Adult)
Low body temperature
Weight gain
Mental retardation
excess GH during pre-puberty
Gigantism
excess GH after growth plates closed
acromegaly
Cushing’s Disease cause
pituitary tumor (excess ACTH)
Type I diabetes also known as
juvenile diabetes, or insulin-dependent diabetes,
is the impaired production of insulin by the pancreas, and is believed to be caused by the destruction of the cells of the islets of Langerhans by autoantibodies (autoimmunity).
Type II diabetes
In type II diabetes, the pancreas secretes normal or low levels of insulin, but the main cause of the high glycemia is the peripheral resistance of the cells to the action of the hormone.