Endocrine- thyroid and parathyroid

Question 1

the thyroid gland consists of closely packed spherical follicles lined by a single layer of cuboidal epithelial cells and filled with _____.

Answer 1

“colloid”

Question 2

Follicle epithelial cell functions (3)

Answer 2

1. Collect and transport iodine to the colloid
2. Synthesize thyroglobulin and secrete
   into colloid
3. Release thyroid hormones from thyroglobulin and secrete them into the circulation

Question 3

what cells secrete calcitonin?

Answer 3

Parafollicular C cells

Question 4

what cells secrete calcitonin?

Answer 4

Parafollicular C cells

Question 5

Follicular Cell Function

Answer 5

1. Synthesize thyroglobulin and thyroid peroxidase, secrete these into the thyroid follicles together with iodine
2. Thyroid peroxidase reduces iodine (makes it reactive), allowing it to integrate onto tyrosine residues of thyroglobulin
3. Follicular cells take up iodinated thyroglobulin from the follicles by endocytosis, extract thyroid hormones by protease action, and release thyroid hormones to the blood

Question 6

_____ function is to produce substrates in which T3 and T4 are going to be generated.

Answer 6

follicular cell

Question 7

_____ function is to produce substrates in which T3 and T4 are going to be generated.

Answer 7

follicular cell