Endocrine System- Pituitary Gland Flashcards
Several processes can disturb the normal activity of the endocrine system, including
impaired synthesis or release of hormones,
abnormal interactions between hormones and
their target
tissues, and abnormal responses of target organs.
Endocrine diseases can be generally
classified as
(1) diseases of underproduction or overproduction of hormones and their resulting
biochemical and clinical consequences and
(2) diseases associated with the development of
mass lesions.
Such lesions might be nonfunctional, or they might be associated with
overproduction or underproduction of hormones.
The pituitary gland is composed of two morphologically and functionally distinct components:
the:
anterior lobe (adenohypophysis) and the posterior lobe (neurohypophysis).
The ____________ constitutes about 80% of the gland.
anterior pituitary
The production of most pituitary hormones is
controlled predominantly by positive-acting releasing factors from the hypothalamus ( Fig. 24-1
), which are carried to the anterior pituitary by a____________________
portal vascular system
The production of most pituitary hormones is
controlled predominantly by positive-acting releasing factors from the hypothalamus ( Fig. 24-1
), which are carried to the anterior pituitary by a portal vascular system.
____________- is the major
exception; its primary hypothalamic control is inhibitory, through the action of dopamine
Prolactin
Pituitary growth hormone also differs in that it receives both stimulatory and inhibitory influences
via the hypothalamus.
In routine histologic sections of the anterior pituitary, a colorful array of
cells is present that contain ____________________
eosinophilic cytoplasm (acidophil), basophilic cytoplasm (basophil), or poorly staining cytoplasm (chromophobe) cells ( Fig. 24-2 ).
Specific antibodies against the
pituitary hormones identify five cell types:
- Somatotrophs,
- Lactotrophs (mammotrophs),
- Corticotrophs
- Thyrotrophs
- Gonadotrophs:
Nmemonics : So CoLa To Go
_____________, producing growth hormone (GH): These acidophilic cells constitute half
of all the hormone-producing cells in the anterior pituitary.
Somatotrophs
_________________, producing prolactin: These acidophilic cells secrete
prolactin, which is essential for lactation.
Lactotrophs (mammotrophs)
Corticotrophs: These basophilic cells produce adrenocorticotropic hormone (ACTH),
pro-opiomelanocortin (POMC), melanocyte-stimulating hormone (MSH), endorphins,
and lipotropin
Corticotrophs
_____________: These pale basophilic cells produce thyroid-stimulating hormone (TSH).
Thyrotrophs
________________ These basophilic cells produce both follicle-stimulating hormone (FSH)
and luteinizing hormone (LH).
FSH stimulates the formation of graafian follicles in the
ovary, andLH induces ovulation and the formation of corpora lutea in the ovary.
The
same two hormones also regulate spermatogenesis and testosterone production in
males.
Gonadotrophs:
Nnemonics:
Acidophils: Somatotrophs
Lactotrophs
ACIDIC ang SOLA
** B- Flat**
FSH
LH
ACTH ( Cotricotrophs)
Thyroid
-