Endocrine system Part 1 Flashcards
What is the difference between exocrine and endocrine glands?
Exocrine glands secrete their products into ducts (e.g., sweat or intestines) whereas endocrine glands are ductless and release hormones into the blood
What is the definition of a hormone?
A chemical messenger carried by the blood to target cells.
What 5 things do hormones help to regulate?
1) Chemical composition and volume of internal environment
2) Metabolism and energy balance
3) Contraction of smooth and cardiac muscle fibres
4) Glandular secretions
5) Some immune system activities
Other than regulation of different factors in the body, what are the 3 other functions of hormones?
Control growth and development
Regulate operation and reproductive system
Help establish circadian rhythm
Hormones operate in synchrony with the nervous system. Compare endocrine and the nervous system.
Endocrines are chemical messengers whereas the nervous system is an electrical conduit system
The nervous system acts instantaneously whereas endocrine acts slower (relatively)
Endocrine often has longer lasting effects whereas nervous system has short-lived response
What are the 3 major structural classes hormones fall into?
1) Amines (e.g., thyroid hormones, catecholamines)
2) Peptides and proteins (e.g., insulin)
3) Steroid (e.g., testosterone (largely derived of cholesterol))
What 2 major organs remove hormones from the blood plasma by metabolizing or excreting them?
Liver and Kidneys
What 2 types of hormones are water soluble and circulate dissolved in plasma?
Peptide and catecholamine
What 2 types of hormones circulate bound to plasma proteins
Steroid and thyroid hormones
What 3 things do the responsiveness of a target cell to a hormone depend on?
1) Hormone concentration in blood
2) Abundance of target cell’s hormone receptors
3) Influences exterted by other hormones
What 3 types of effects can hormonal interactions have?
Permissive - when the action of one hormone requires another hormone to stimulate a response
Synergistic - when 2 hormones act together to create a greater effect on each other
Antagonistic - e.g., insulin and glucagon
What 3 factors is hormone secretion controlled by?
1) Plasma concentration of an ion or nutrient that the hormone regulates
2) Neural input to the endocrine cells
3) Other hormones