Endocrine System Flashcards

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1
Q

What is a hormone?

A

a chemical that is secreted by an endocrine gland and that affects the functioning of a cell or organ; often carried in the blood

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2
Q

What is the difference between an endocrine and exocrine gland?

A

Exocrine glands: have ducts, secrete onto the body surface or a body cavity, secrete near the site of release, eg: mammary glands, mucuous glands, tear glands, sweat glands)
Endocrine glands: no ducts, secrete into extracellular fluid of the body, release to target cells, travel in the blood, eg: pituitary, pancreas, adrenal cortex

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3
Q

Define the endocrine system?

A

The body system involved in chemical communication to cells

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4
Q

Define the process in which steroidal cells have an impact on the cells

A

lipid soluble, able to pass through phospolipid bi-layer and into the cell, combine with a receptor protein in the cell (such as mitochondria, nucleus etc) to form a hormone receptor compex and activate genes controlling the formation of particular proteins

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5
Q

Define the process in in which non steroidal cells have an impact on the cells.

A

not lipid soluble, attach to protein receptors on the outside of cells, secondary messenger is sent to diffuse through the cell and activate particular enzymes

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6
Q

what is the difference between a steroidal and non steroidal hormone?

A

steroidal: lipid soluble, able to pass through cell membrane and activate receptors
non steroidal: not lipid soluble, have to attach to receptor proteins on the surface of membrane which send secondary messengers to activate enzymes

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7
Q

How do hormones produce a desired effect?

A
  • activate certain genes in the nucleus so a particular enzyme or structural protein is produced
  • change the shape or structures of an enzyme so that it is turned on or off
  • change the rate of production of an enzyme or structural protein by changing the rate of transcription or translation during production
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8
Q

Function, target cells: oxytocin

A

uterus + mammary glands. Stimulates contraction of uterus during childbirth, release of milk from mammary glands (milk let-down reflex)

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9
Q

Function, target cells: anti-diuretic hormone

A

kidneys. Increases water re-absorption so less is lost as urine

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10
Q

Function, target cells: growth hormone

A

most cells. Increases rate of growth of cells and protein synthesis

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11
Q

Function, target cells: adrenocorticotropic hormone

A

adrenal cortex. Stimulates secretions of hormones from adrenal cortex

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12
Q

Function, target cells: follicle stimulating hormone

A

Ovaries, testes. stimulates development of ovarian follicle/sperm.

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13
Q

Function, target cells: luitenizing hormone

A

ovaries, testes. Ovulation and maintenance of corpus luteum, secretion of testosterone

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14
Q

Function, target cells: prolactin

A

mammary glands. Stimulates milk production

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15
Q

Function, target cells: thyroid stimulating hormone

A

thyroid gland. Stimulates secretion of hormones from the thyroid.

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16
Q

Secreted from, function, target cells: thyroxine

A

Secreted from thyroid. Target cells: most. Increases metabolic rate.

17
Q

Secreted from, function, target cells: parathyroid hormone

A

Secreted from parathyroid. Target cells: bones, kidneys. Increases levels of calcium in the blood

18
Q

Secreted from, function, target cells: thymosins

A

Secreted from thymus. Target cells: T lymphocytes. Stimulate maturation of T lymphocytes.

19
Q

Secreted from, function, target cells: aldosterone

A

Secreted from adrenal cortex. Target cells: kidneys. increases reaborption of sodium ions and excretion of potassium ions

20
Q

Secreted from, function, target cells: cortisol

A

Secreted from adrenal cortex. Target cells: most. Promotes normal metabolism, helps body deal with stress, promote repair of damaged tissue

21
Q

Secreted from, function, target cells: adrenaline and noradrenaline

A

Secreted from: adrenal medulla. Target cells: most. Prepares body for fight or flight response, reinforces effects of sympathetic nervous system

22
Q

Secreted from, function, target cells: insulin

A

Secreted from: pancreas. Target cells: most. Lowers blood glucose levels.

23
Q

Secreted from, function, target cells: glucagon

A

Secreted from: pancreas. Target cells: liver and fat storage tissues. Increases blood glucose levels.

24
Q

Secreted from, function, target cells: androgens

A

Secreted from: testes. Target cells: many. Stimulates sperm production, growth of skeleton and muscles, male sex characteristics

25
Q

Secreted from, function, target cells: oestrogen

A

Secreted from: ovaries. Target cells: many. Stimulates development of female characteristics, regulates menstrual cycle

26
Q

Secreted from, function, target cells: progesterone

A

Secreted from: ovaries. Target cells: uterus and mammary glands. Regulates menstrual cycle and pregnancy, prepares mammary glands for milk secretion