Endocrine System Flashcards
What is a hormone?
a chemical that is secreted by an endocrine gland and that affects the functioning of a cell or organ; often carried in the blood
What is the difference between an endocrine and exocrine gland?
Exocrine glands: have ducts, secrete onto the body surface or a body cavity, secrete near the site of release, eg: mammary glands, mucuous glands, tear glands, sweat glands)
Endocrine glands: no ducts, secrete into extracellular fluid of the body, release to target cells, travel in the blood, eg: pituitary, pancreas, adrenal cortex
Define the endocrine system?
The body system involved in chemical communication to cells
Define the process in which steroidal cells have an impact on the cells
lipid soluble, able to pass through phospolipid bi-layer and into the cell, combine with a receptor protein in the cell (such as mitochondria, nucleus etc) to form a hormone receptor compex and activate genes controlling the formation of particular proteins
Define the process in in which non steroidal cells have an impact on the cells.
not lipid soluble, attach to protein receptors on the outside of cells, secondary messenger is sent to diffuse through the cell and activate particular enzymes
what is the difference between a steroidal and non steroidal hormone?
steroidal: lipid soluble, able to pass through cell membrane and activate receptors
non steroidal: not lipid soluble, have to attach to receptor proteins on the surface of membrane which send secondary messengers to activate enzymes
How do hormones produce a desired effect?
- activate certain genes in the nucleus so a particular enzyme or structural protein is produced
- change the shape or structures of an enzyme so that it is turned on or off
- change the rate of production of an enzyme or structural protein by changing the rate of transcription or translation during production
Function, target cells: oxytocin
uterus + mammary glands. Stimulates contraction of uterus during childbirth, release of milk from mammary glands (milk let-down reflex)
Function, target cells: anti-diuretic hormone
kidneys. Increases water re-absorption so less is lost as urine
Function, target cells: growth hormone
most cells. Increases rate of growth of cells and protein synthesis
Function, target cells: adrenocorticotropic hormone
adrenal cortex. Stimulates secretions of hormones from adrenal cortex
Function, target cells: follicle stimulating hormone
Ovaries, testes. stimulates development of ovarian follicle/sperm.
Function, target cells: luitenizing hormone
ovaries, testes. Ovulation and maintenance of corpus luteum, secretion of testosterone
Function, target cells: prolactin
mammary glands. Stimulates milk production
Function, target cells: thyroid stimulating hormone
thyroid gland. Stimulates secretion of hormones from the thyroid.