Endocrine System Flashcards
Pituitary Gland
"”Master Gland””: Two parts (neurohypophysis [posterior], adenohypophysis [anterior])
Pituitary Gland location
Hangs from hypothalmus, protected by sella turcica of the sphenoid bone
Posterior pituitary gland (Neurohypophysis)
Stores ADH (vasopressin) and Oxytocin, releases when neural impulses arrive from hypothalamus. Hypothalamus produces neurohypophyseal hormones and transports them for storage in the posterior pituitary.
Anterior pituitary gland (Adenohypophysis)
Produces GH, TSH, ACTH, prolactin, FSH, LH, and other releasing hormones. Larger than posterior lobe. Only lobe to produce hormones (posterior only STORES hormones from hypothalamus)
ADH
Antidiuretic hormone, or “Vasopressin”, maintains BP by reabsorption of water by kidney tubules and vasoconstriction
Oxytocin
Stimulates contraction of uterus and release of milk. Fx by way of positive feedback loops. Produced in hypothalamus and stored in the posterior pituitary.
Hormone
Chemical substance secreted by a gland into the BLOODSTREAM that controls another gland or body system (“target”).
Diuresis
Increased or excessive formation of urine
Amines
Variations of thyrosine, include thyroxin, epi, and nor-epi
Proteins
Chains of amino acids, insulin, growth hormone, and calcitonin
Steroids
Made of cholesterol, cortisol, aoldosterone, estrogen, progesterone, and testosterone. Lipid-soluble.
Most hormones work on this feedback mechanism
Negative feedback mechanism (Oxytocin is an exception, and in cases of BP regulation)
What do endocrine glands respond to?
Blood level changes or other hormones present in the blood stream
Hypothalmus
Produce Oxytocin and ADH/vasopressin.
Releasing hormones for anterior pituitary
Pineal Gland
aka “Epiphysis”
Produces Melatonin
Thymus Gland
T-cell maturation
Huge when we’re born and gets smaller with age
Anterior superior mediastinum: in front of heart and behind sternum
Pancreas
**Insulin: **secreted by beta cells in re: high blood sugar; fx to decrease blood sugar
**Glucagon: **secreted by alpha cells in re: low blood sugar; fx to increase blood sugar
Ovaries
Estrogen, progesterone, and Inhibin
Reabsorption
"”Put it back in the blood stream””
Parathyroid Glands
PTH: parathyroid hormone can increase calcium in blood stream. They are found behind the thyroid, pea shaped and can have 3-6 other them.
Adrenal (suprarenal) Glands
Cortex: Aldosterone, cortisol, sex hormones
Medulla: Epi and Nor-epi
Testes
Testosterone, Inhibin
Adrenocorticotropic Hormone (ACTH)
Produced in anterior pituitary, often in Re: to biological stress
Increases secretion of cortisol by the adrenal glands
T3 and T4
Triiodothyronine and Thyroxin: Increase energy production and rate of protein synthesis
Thryroid hormones
Regulation of metabolism
GH
Growth Hormone: Increases mitosis, amino acid transport into cell, protein synthesis, and use of fats for energy
Thyroid Gland location
Front and sides of trachea, the two lobes are connected by isthmus (bridge across trachea)
Thyroid Gland
Produces T3, T4, and calcitonin (regulates calcium when calcium level too high ““calcitone it down””)
Another name for a tumor
Neoplasm
Graves Disease
Hyperthyroidism: Abnormal thyroid stimulating mechanism, increased iodide uptake, thyroid metabolism, growth, and secretion of hormone
Thyrotoxic Crisis (thyroid storm)
worsening of a thyrotoxic state, possible death within 48 hours (no way to stop thyroid from releasing hormone, we can only sedate them)
The hormone that lowers blood glucose level by enabling cells to take glucose in
Insulin
The hormone that increases the rate of cell division
Growth Hormone
Pancreas
Endocrine functions: islets of langerhans have three types of cells; Alpha (glucagon), Beta (insulin), and Delta