Endocrine System Flashcards
Mechanism and regulation of hormones, glands of the endocrine system and hormones
What is an exocrine gland?
glands are ducted (such as sweat, and saliva) and are not a part of the endocrine system
What is an endocrine gland?
Ductless glands that secrete hormones into the blood.
What is a target cell?
A cell that has specific receptors for a particular hormone.
How does the endocrine system differ from the nervous system?
The endocrine system communicates and controls via hormone secretion, a slower, longer-lasting type of control than nerve impulses.
What are non-steroid hormones?
These are “first messengers” that bind to receptors on the target cell membrane, triggering intracellular “second messengers” such as cyclic AMP to affect the cell’s activities.
What are steroid hormones?
Primary effects are produced by binding to receptors within the target cell nucleus; they influence cell activity by acting on DNA - a slower process than non-steroid action.
What is negative feedback?
A mechanism that reverses the direction of a change in a physiologic system.
What is positive feedback?
A mechanism that amplifies a physiologic change (uncommon).
What are prostaglandins?
Powerful lipid substances found in a wide variety of body tissues. Typically produced in a tissue and diffuse only a short distance to act on cells in that tissue. Often called “tissue hormones” or “paracrine agents”.
Describe the anterior pituitary gland.
Made up of glandular epithelium. (also called adenohypophysis)
Describe the posterior pituitary gland.
Made up of nervous tissue. (also called neurohypophysis)
Where is the pituitary gland located?
In a bony depression (sella turica) of sphenoid bone in the skull. Connected to the hypothalamus by a pituitary stalk.
Name the 6 major hormones of the anterior pituitary gland (adenohypophysis).
1) Thyroid-stimulating hormone (TSH)
2) Adrenocorticotropic hormone (ACTH)
3) Follicle-stimulating hormone (FSH)
4) Luteinizing hormone (LH)
5) Growth hormone (GH)
6) Prolactin (PRL) (lactogenic hormone)
What is the function of TSH (thyroid-stimulating hormone)?
Stimulates growth of the thyroid gland; also stimulates it to secrete thyroid hormone. (anterior pituitary)
What is the function of ACTH (adrenocorticotropic hormone)?
Stimulates growth of the adrenal cortex and prompts it to secrete glucocorticoids (GCs) (mainly cortisol) (anterior pituitary)
What is the function of FSH (follicle-stimulating hormone)?
In females: initiates growth of ovarian follicles each month and stimulates estrogen secretion.
In males: stimulates sperm production. (anterior pituitary)
What is the function of LH (luteinizing hormone)?
Acts with FSH to stimulate estrogen secretion and follicle growth to maturity; causes ovulation; causes luteinization of the ruptured follicle and stimulates progesterone secretion by the corpus luteum.
Causes the testes to secrete testosterone in males. (anterior pituitary)
What is the function of GH (growth hormone)?
Stimulates growth by accelerating protein anabolism; accelerates fat catabolism; slows glucose catabolism, thereby increasing blood glucose levels (hyperglycemia). (anterior pituitary)
What is the function of PRL (prolactin)?
Also called lactogenic hormone; stimulates breast development during pregnancy and secretion of milk after delivery of baby. (anterior pituitary)
Name the hormones of the posterior pituitary gland (neurohypophysis)
Antidiuretic hormone (ADH)
Oxytocin (OT)
What is the function of ADH (antidiuretic hormone)?
Accelerates water reabsorption from urine in the kidney tubules into the blood, thereby decreasing urine secretion. (posterior pituitary)