ENDOCRINE SYSTEM Flashcards
iodothyronines are derived from
tyrosine
melatonin and serotonin are derived from
tryptophan
examples for amines
iodothyronines, melatonin, and serotonin
catecholamines are derived from
tyrosines
catecholamines examples
adrenaline and noradrenaline
steroid hormones
fat-soluble hormones, derived from cholesterol
steroid hormones examples
adrenocorticoids, gonadal hormones
most abundant type of hormones
peptide hormones
water-soluble hormones
peptide hormones
proteinous hormones
100-200 AA
Proteinaceous hormones examples
TSH, GH, GSH, hCG, hPL, Relaxin, gastrointestinal hormone
polypeptide hormones
30-100 AA
Short peptide
3-9 AA
Fatty acid-derived hormones examples
prostaglandin
glands derived from ectoderm?
hypothalamus, pituitary gland, pineal gland, adrenal medulla
glands derived from mesoderm?
gonads
glands derived from endoderm?
thyroid, parathyroid, thymus, pancreas, adrenal cortex
anterior pituitary secretes how many hormones?
6 trophic hormones
glands that are not under the direct control of the pituitary?
parathyroid, thymus, pancreas, pineal gland and adrenal medulla
growth hormone functions
increases the glucose levels in the blood by lipolysis of adipocytes and decreasing the insulin level. Increases the amino acid level in the blood
prolactin is also known as
mammotropic hormone, luteotrophin,
the degeneration of the anterior lobe of the pituitary causes a disease called
Simmonds disease or acromicria
functions of melatonin
the biological clock, maintains body temperature, metabolism, pigmentation, and defense mechanisms of the body. it inhibits ovarian functions and delays sexual maturity
largest endocrine gland in the body
thyroid
two lobes of the thyroid contain
3 million follicles and stromal tissue
functions of thyroxines
controls BMR, cell respiration, metabolism of proteins, fats, and carbohydrates, stimulates erythropoiesis, influences the working of kidney tubules, promotes protein synthesis, maintains body temperature, and regulate menstrual cycle
hypothyroidism in children
cretinism
hypothyroidism in adults
myxoedema or gull disease
Hashimoto’s disease
degeneration of the thyroid gland
thyrocalcitonin is a
hypocalcemic hormone
para calcitonin is a
hypercalcemic hormone
adrenal cortex is divided into
zona glomerulosa, zona fasciculata, zona reticularis
mineralocorticoids are secreted by
zona glomerulosa
hyposecretion of mineralocorticoids causes
addison’s disease
hypersecretion of mineralocorticoids causes
aldosteronism or Conn’s disease
most abundant type of corticosteroids
glucocorticoids
most important glucocorticoids?
cortisol
stress hormone
cortisol
glucocorticoids are primarily involved in
carbohydrate, protein, and fat metabolism and also promote glycogenolysis, proteolysis, lipolysis, and promote gluconeogenesis. it also promotes erythropoiesis and creates anti-allergic responses.
hyposecretion of cortisol
Addison’s disease
hypersecretion of cortisol
Cushing’s disease
intracellular hormonal action is shown by
fat-soluble steroids or lipophilic hormones and iodothyronines
extracellular hormonal action is shown by
water-soluble hydrophilic hormones such as catecholamines and peptide hormones, growth factors
secondary messengers are
cyclin AMP, Calcium ions, Diacyl Glycerol(DG), inositol triphosphate