Endocrine System Flashcards
Pea-sized
Aka hypophysis
It is suspended from the base of the brain by a stalk called INFUNDIBULUM
Pituitary Gland
Butterfly-shaped
Thyroid gland
Tiny masses of glandular tissue
Parathyroid gland
Tringular-shaped glands
Adrenal glands
Little masses
Pancreatic Islets or Islets of Langerhans
Small, cone-shaped
Resembles a pine nut
Pineal Gland or Pineal Body
Mostly fibrous, connective tissue, or fat
Thymus Gland
Almond-shaped
Ovaries (gonad)
Oval pair
Testes (gonad)
Inferior to the hypothalamus and surrounded by Turk’s Saddle (Sella Turcica)
Pituitary Gland
Base of the neck or inferior to the Adam’s Apple
Near the thyroid cartilage of larynx
Thyroid Gland
Posterior surface of the thyroid gland
Parathyroid gland
Sit on top of the kidneys
Adrenal glands
Scattered among the acinar tissues of the pancreas
Pancreatic Islets
Hangs from the third ventricle roof
Develops from the diencephalon of the brain
Pineal Gland
Posterior to the sternum
Thymus gland
Located at pelvis
Ovaries (gonad)
Located at scrotum
Testes (gonad)
Hormones produced in the anterior pituitary gland
- Growth Hormone (GH
- Prolactin (PRL)
- Adrenocorticotropic Hormone (ACTH) - tropic hormone
- Thyroid-stimulating hormone/Thyrotropic hormone (TSH/TH) - tropic hormone
- Follicle-stimulating hormone (FSH) - gonadotropic
- Luteinizing Hormone (LH) - gonadotropic
Hormones produced in posterior pituitary gland
- Oxytocin
- Antidiuretic Hormone (ADH) or Vasopressin
Hormones produced in thyroid gland
- Thyroid hormone
a. Thyroxine (T4)
b. Triiodothyronine (T3) - Calcitonin
Hormone produced in parathyroid gland
Parathyroid hormone (PTH)
Hormones produced in adrenal glands
- Mineralocorticoids (aldosterone)
- Glucocorticoids (cortisone&cortisol)
- Gonadocorticoids (sex hormones)
Hormone produced in pancreatic islets
- Insulin - produced by beta cells
- Glucagon - produced by alpha cells
-Inhibitory hormone produced in pineal gland
-Regulates circadian rhythms
-inhibits release of hormones in the hypothalamus that stimulate the production of sex hormones
-has depressing effect
-“hormone of the darkness” as it is produced during times of low light levels.
Melatonin
(Sleep hormone)
Hormone produced in thymus gland
Thymosin
Hormone produced in gonads
Female
1. Estrogen
2. Progesterone
Male
1. Androgens
2. Testosterone
Major Endocrine Organs
- Pituitary Gland
- Thyroid Gland
- Parathyroid Gland
- Adrenal Gland
- Pancreatic Islets
- Pineal Gland
- Thymus Gland
- Gonads
Major metabolic hormone
Secretes active iodine containing hormones
Thyroid hormone
Major hormone with 4 iodine atoms
Thyroxine T4
3 iodine atoms
Triiodothyronine (T3)
Hypocalcemic hormone
Calcitonin
-Most important Ca ion regulator
-hypercalcemic hormone
Parathyroid gland
-Produces costicosteroids
(Steroid hormones)
-stimulates by SNS to secrete “catecholamines”
(Epinephrine or adrenaline, Norepinephrine or noradrenaline)
-Adrenal Cortex
-Adrenal Medulla
Inhibits aldosterone release
Mineralocorticoids
Hyperglycemic hormone
-Glucocorticoids, cortisone, or cortisol
-Glucagon
Mostly androgen and some estrogen in relatively small amounts
Gonadocorticoids/Sex hormones
The only hypoglycemic hormone
Insulin
Target: skeletal muscles, long bones, most tissues (non-endocrine)
Growth hormone
Target: Mammary glands (non-endocrine)
Prolactin
(Luteotropin)
(endocrine)
Target: adrenal cortex (outer portion)
Adrenocorticotropic Hormones
(endocrine)
Target: thyroid gland
Thyroid stimulating hormone/thyrotropic hormone
Target: ovaries, testes
FSH
Target: ovaries, interstitial cells of the tested
LH
Target: uterus, breast
Oxytocin
Target: kidney, arterioles
Antidiuretic hormone/vasopressin
Target: every body cell
Thyroid hormone
Target: skeleton
Calcitonin
Target: skeleton and kidney and intestines
Parathyroid hormone (PTH)
Target: kidney tubules
Mineralocorticoids
Target: body cells
Glucocorticoids
Target: sex organs
Gonadocorticoids
Target: heart, blood vessels, liver, lungs, brain, muscles
Catecholamines secreted by adrenal medulla
Target: body cells (esp. liver, skeletal muscle, adipose tissue)
Insulin
Target: primarily liver
Glucagon
Target: primarily brain
Melatonin
Target: white blood cells
Thymosin
Target: reproductive organs
Estrogen, progesterone, androgen, testosterone
-glandular tissue in adrenal gland
-neural tissue in adrenal gland containing 3 distinct layers
Adrenal cortex
Adrenal medulla
Cell types in thyroid glands
- Follicular cells
- Parafollicular cells
Features of thyroid gland
- Has two loves
- Loves connected by isthmus
- Contains follicle
-In pituitary gland, this part is made up of glandular tissue
-In pituitary gland, this part is made up of neural tissue
Anterior PG
Posterior PG
Causes growth in size and proliferation of skeletal muscles and tissues.
Fat breakdown WITHOUT glucose
Maintains blood sugar HOMEOSTASIS
(increase blood sugar)
Growth Hormone
Milk production in pregnant women
Prolactin
Adrenal cortex regulation
Adrenocorticotropic Hormone
Thyroid gland growth & activity regulation
TSH
Follicle development and maturity in females and sperm dev’t in men
FSH
Ovulation/Testosterone production
LH
Strong uterine contractions during sex, labor, and breastfeeding
Milk ejection
Oxytocin
-Urine production inhibition
Kidneys reabsorb more water
Put decrease to urination
And increase in blood volume
-vasoconstriction
ADH/vasopressin
Causes biological rhythm regulation
Melatonin
Causes lymphocytes’ normal decevelopment
White blood cells
Reduces blood glucose levels, increase glucose uptake by cells
Insulin
Increase glycogen breakdown to glucose
Glucagon
General name for organs producing hormones
Glands
Regions that are receptive to hormones
Target areas
Secretes melatonin
Pineal gland
Stores ADH
Posterior PG
Produce TSH
Anterior PG
Stimulates thyroid glands to produce thyroid hormones
Where is glucagon produced?
Pancreas
Blood glucose level regulation
Hormones in adrenal glands controlling water and electrolyte balance
Corticosteroid hormones
Secrete epinephrine
Adrenal
Consists of glands that produce chemical messengers called hormones that are picked up by blood capillaries (ductless secretion)
Endocrine systems
Aids in METABOLISM (GLUCOSE), body heat regulation, and normal tissue growth and development (REPRODUCTIVE/NERVOUS SYSTEM)
Thyroid hormone
Lowers blood calcium level by Calcium deposition into the bones (Ca is stored in bones) in response to increasing levels
Calcitonin
Increases bone destruction& consequently releases of Ca into the blood from bones, thereby increasing Calcium blood levels
Parathyroid (skeleton as target)
Increase absorption of calcium from the urinary filtrate and foods, respectively. Also aids in stimulation of vitamin D production in kidneys
Parathyroid hormone (targets:Kidney and intestines)
-development of female sex characteristics
-together with progesterone, breast development and cyclic changes in the uterine lining
Estrogen
-Acts with estrogen, menstrual cycle
-during pregnancy, uterine muscle relaxation & breast tissue development
Progesterone
-Puberty: growth & maturation of reproductive organs, male secondary sex characteristics & male drive stimulation
-adults: continuous sperm production
Androgens, testosterone
Increases sodium and consequently water retention (water follows Na), and increases potassium excretion into the urine. As a result, blood volume and blood pressure increase
Mineralocorticoids on kidney tubules
-Cell metabolism, resistance to long-term stressors during the resistance stage by increasing blood glucose levels (increase glucose synthesis from aa)
-suppresion of inflammation/immune system
Glucocorticoids on body cells
Cope up with short term stress during alarm stage; SNS effects:
-increased heart rate
-increased bp
-increased conversion of glycogen to glucose-BRONCHODILATION
-increase blood flow to the brain
-increased alertness
-devreased bloodflow to digestive and urinary
-increased metabollic rate
Catecholamines from stimulation of adrenal medulla by SNS
Glands that secrete materials in tubules.or ducts
Exocrine glands
Highways to carry hormone throughout the body
Interstitial fluid and blood vessels
Many hormone regulate the internal environment of the body in a homeostatic response:
Negative feedback loop
Has a major role in controlling endocrine functions. Secretes both stimulating and inhibitory hormones
Hypothalamus
Originates from the roof of oral cavity during embryonic development.
(3parts?)
Anterior Pituitary Gland
(Adenohypophysis- composed of epithelial cells)
1. Pars tuberalis
2. Pars intermedia
3. Pars distalis
Hormones that stimulate the growth and control the function of gonads
Gonadotropins
Aka neurohypophysis
Composed of nervous tissue
Hormones released from this are secreted by hypothalamus and flow thru axon to be stored in ….
Posterior Pituitary Gland