Endocrine Secondary Messengers Flashcards

1
Q

Dopamine

A

Gi in Lactotrophs

Variety of G-pcrs elsewhere.

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2
Q

Prolactin

A

Tyrosine Kinase

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3
Q

ADH

A

V1 Receptors: Gq

V2 Receptors: Gs

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4
Q

Oxytocin

A

Gq in Uterine Smooth Muscle

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5
Q

GHRH (Growth Hormone Releasing Hormone)

A

Gs in Somatotrophs

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6
Q

Somatostatin (Growth Hormone Inhibiting Hormone)

A

Gi in Somatotrophs

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7
Q

Growth Hormone

A

Tyrosine Kinase

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8
Q

Serotonin (5-Hydroxytryptamine)

A

Variety of G-pcrs

Also Ligand-gated ion channels

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9
Q

T3 (active Thyroid Hormone)

A

Intracellular Receptor

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10
Q

Aldosterone

A

Intracellular Receptor

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11
Q

Cortisol

A

Intracellular Receptor

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12
Q

Androgens (DHEA, Androstenedione, Testosterone, Dihydrotestosterone, Estradiol)

A

Intracellular Receptor

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13
Q

Angiotensin II

A

Gq in Zona Glomerulosa

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14
Q

ACTH

A

Gs in Zona Reticularis and Zona Fasciculata

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15
Q

CRH (Corticotropin Releasing Hormone)

A

Gs in Corticotropes

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16
Q

Acetylcholine (in Adrenal Medulla)

A

Ligand gated sodium channels

17
Q

TRH (Thyroid Releasing Hormone)

A

Gq in Thyrotrophs

18
Q

TSH

A

Gs in Thyroid follicular cells

19
Q

Glucagon

A

Gs in target tissues

20
Q

Insulin

A

Tyrosine Kinase

21
Q

Ca 2+

A

Gq in Parathyroid Chief Cells

22
Q

PTH

A

Unclear? in Osteoblasts

Gs in Proximal Tubule Cells

23
Q

Vitamin D3

A

Intracellular Receptor

24
Q

GnRH (Gonadotropin Releasing Hormone)

A

Gq in Gonadotrophs

25
Q

LH

A

Gs in Leydig Cells of Testes

26
Q

FSH

A

Gs in Sertoli Cells of Testes