Endocrine regulation of Male reproductive tract Flashcards
what is the process of sperm synthesis called and where does it occur
spermatogenesis, occurs in the testes
how long does the full spermatogenic process take
70days
describe how many sperm are estimated to be produced and over how many years
around 1000 every heart beat, from puberty for over 60 years
what do the testes consist of
seminiferous tubules surrounded by interstitial tissue(Leydig cells, blood vessels, leukocytes, fibroblasts)
what are the endocrine and paracrine factors affecting the male reproductive system
endocrine = LH and FSH paracrine = testosterone and inhibin
what cells secrete testosterone
Leydig cells
what types of cells are found in the seminiferous tubules
Sertoli cells and germ cells
what is the action of FSH in the male reproductive system
stimulates spermatogenesis(along with testosterone)
what is the action of LH in he male reproductive system
stimulates testosterone secretion from Leydig cells
describe the action of inhibin
decreases FSH secretion
what are the functions of testosterone in the testes
maintains integrity of blood-testes barrier, stimulates release of mature spermatozoa from Sertoli cells(by influencing peritubular myoid cells)
where is testosterone released to
the testes and in the circulation
wat is the function of testosterone in the circulation
negative feedback reducing release of GnRH and LH
what is secreted by the Sertoli cells
androgen binding globulin(ABG) and inhibin
