Endocrine - Physiology Flashcards
1
Q
A
2
Q
What are the different steps and names during the synthesis of insulin?(9 points)
A
Preproinsulin is synthesized in the rough endoplamic reticulum. The pre-signal is cleaved. The proinsulin is stored in secretory granules. This is followed by cleavage of proinsulin.** Exocytosis** of insulin and C-peptide occur equally.
3
Q
Insulinoma is characterized by an increase in what?(2 points)
A
C-peptide and insulin
