Endocrine I: Pituitary, Pineal, and Medulla Flashcards

1
Q

What are exocrine glands?

A

Glands with ducts that secrete non-hormones via ducts onto epithelial surfaces

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2
Q

What part of the cranium houses the pituitary gland?

A

The sella turcica

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3
Q

What controls secretion of pituitary hormones?

A

The hypothalamus

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4
Q

From what is the posterior pituitary derived? What is its alternate name based on this?

A

Derived from a downgrowth of neuroectoderm– aka neurohypophysis

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5
Q

From what does the anterior pituitary develop?

A

An upgrowth of the roof of the primitive oral cavity called Rathke’s pouch

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6
Q

What are the subdivisions of the anterior pituitary?

A

Pars distalis, pars tuberalis, pars intermedia

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7
Q

What are the subdivisions of the posterior pituitary?

A

Pars nervosa and infundibulum

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8
Q

What are the functions of the posterior pituitary? what hormones does it contain?

A

Storage of oxytocin and ADH produced in the hypothalamus

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9
Q

What is the hypothalamo-hypophyseal tract?

A

Axons from paraventricular and supraoptic nulcei of the hypothalamus extending into the pars nervosa, where they release hormones

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10
Q

Where, specifically, is antidiuretic hormone (vasopressin) produced? Oxytocin?

A

ADH- supraoptic nucleus of the hypothalamus; Oxytocin- produced in the paraventricular nucleus of the hypothalamus

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11
Q

True or False: Axons within the neurohypophysis with secretory activity are myelinated

A

False

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12
Q

What glial cells support neurons within the posterior pituitary?

A

Pituicytes

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13
Q

What is the most numerous cell of the neurohypophysis?

A

Pituicytes

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14
Q

What are Herring bodies?

A

Swellings within axons of the posterior pituitary, which are sites of storage for neurosecretory material

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15
Q

What kind of hormone is primarily secreted by the anterior pituitary?

A

Tropic hormones

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16
Q

Histologically, what are the different types of cells in the pars distalis?

A

Chromophils (acidophils and basophils) and Chromophobes

17
Q

What is the primary mechanism for regulating anterior pituitary hormone release?

A

Releasing and inhibitory factors released from the hypothalamus?

18
Q

How are releasing and inhibiting factors from the hypothalamus transported to the anterior pituitary?

A

Hypophyseal portal system

19
Q

What is a portal system?

A

A vascular system where blood travels from one capillary bed to another through a vein without first traveling to the heart?

20
Q

What is the narrow zone of tissue between the pars distalis and the pars nervosa?

A

Pars intermedia

21
Q

What is an adenoma?

A

Benign tumors of glandular origin

22
Q

What is the outermost layer of the adrenal gland?

A

A dense connective tissue capsule

23
Q

What are the developmental origins of the suprarenal gland?

A

Cortex is derived from mesoderm; medulla is derived from neural crest cells

24
Q

What supplies blood to the adrenal glands? What supplies the cortex and medulla?

A

Superior, middle and inferior suprarenal aa which form a subcapsular plexus; short cortical arteries supply the cells of the adrenal cortex and long cortical arteries supply the medulla

25
What are the layers of the adrenal cortex from outside to the inside?
Zona glomerulosa, zona fasciculata, and zona reticularis
26
What hormones are produced by the zona glomerulosa?
Mineralocorticoids, esp. aldosterone
27
What is the primary product of the zona fasciculata?
Glucocorticoids, esp cortisol
28
Why are cells of the zona reticularis more heavily stained than those of the other zones?
They contain fewer lipid droplets and more lipofuscin pigment
29
What is secreted by the zona reticularis?
Androgens
30
How do mitochondria of the adrenal cortex look ?
Spherical
31
What is the predominant cell type of the adrenal medulla? What hormone does it release?
Chromaffin cells; epinephrine (80%) and norepinephrine (20%)
32
What is the embryological origin of the chromaffin cells?
Neural crest cells
33
What innervates chromaffin cells?
Preganglionic sympathetic neurons
34
How does the pineal gland develop? What is its purpose?
It develops as an evagination of the posterior wall of the third ventricle and remains attached to the brain by a short stalk
35
What two types of cells are located within the pineal gland?
Pinealocytes and neuroglial cells
36
What cells release melatonin?
Pinealocytes
37
What is the histologic feature that is characteristic of the pineal gland? What is it?
Corpora arenacea- deposits composed of concentric layers of calcium and magnesium phosphate in an organic matrix