Endocrine: Exocrine Pancreatic Enzymes

Question 1

What are pancreatic enzymes taken for?

Answer 1

To replace missing or deficient normal pancreatic enzymes.

Question 2

What do pancreatic enzymes do to the body?

Answer 2

Effect duodenum and upper jejunum

Question 3

What are the pancreatic enzymes?

Answer 3

1. Trypsin
2. Amylase
3. Lipase to digest
   fats.

Question 4

What is the effect of enzymes on the duodenum and upper jejunum? Digestion

Answer 4

Digestion

Question 5

What does Trypsin digest?

Answer 5

Proteins

Question 6

What does Amylase digest?

Answer 6

Carbohydrates

Question 7

What does Lipase digest?

Answer 7

Fats

Question 8

What conditions are pancreatic enzymes indicated?

Answer 8

1. Pancreatitis
2. Pancreatic cancer
3. Cystic fibrosis
4. Following gastric resection/bypass.
5. Steatorrhea

Question 9

What is Steatorrhea ?

Answer 9

1. A disorder of fat metabolism

2. Characterized by fatty, foul-smelling stools

Question 10

When should pancreatic enzymes be administered?

Answer 10

Before meals

Question 11

Why should pancreatic enzymes be administered before meals?

Answer 11

Ensures that the drug is available in the small intestine to help digestion

Question 12

What drugs do pancreatic enzymes interact with?

Answer 12

1. Antacids
2. Calcium supplements
3. Magnesium supplements
4. Dairy products
5. Folic acid
6. Iron
7. Acarbose
8. Miglitol

Question 13

What is the result of taking pancreatic enzymes with Antacids?

Answer 13

reduces effects of pancreatic enzymes

Question 14

What is the action taken when considering administering pancreatic enzymes with Antacids?

Answer 14

Don’t give together

Question 15

What is the result of taking pancreatic enzymes with Calcium supplements?

Answer 15

reduces effects of pancreatic enzymes

Question 16

What is the action taken when considering administering pancreatic enzymes with Calcium supplements?

Answer 16

Don’t give together

Question 17

What is the result of taking pancreatic enzymes with Magnesium supplements?

Answer 17

reduces effects of pancreatic enzymes

Question 18

What is the action taken when considering administering pancreatic enzymes with Magnesium supplements?

Answer 18

Don’t give together

Question 19

What is the result of taking pancreatic enzymes with folic acid?

Answer 19

Decreased absorption of folic acid

Question 20

What is the result of taking pancreatic enzymes with iron?

Answer 20

Decreased absorption of iron

Question 21

What is the result of taking pancreatic enzymes with Acarbose?

Answer 21

Reduced effectiveness of Acarbose

Question 22

What is the result of taking pancreatic enzymes with Miglitol?

Answer 22

Reduced effectiveness of Miglitol

Question 23

What are adverse reactions to pancreatic enzymes?

Answer 23

1. Diarrhea
   2, Nausea
2. Abdominal cramping

Question 24

What should be monitored in patients receiving pancreatic enzyme therapy?

Answer 24

1. Bowel Movements
2. Diet
3. Weight
4. Fluid intake
5. Urine output
6. Laboratory studies

Question 25

Why should bowel movements be monitored in patients receiving pancreatic enzyme therapy?

Answer 25

A decrease in the number of bowel movements and | improved stool consistency indicate effective therapy.

Question 26

Why should diet be monitored in patients receiving pancreatic enzyme therapy?

Answer 26

to ensure a proper balance of fat, protein, | and starch intake

Question 27

Why is it important to ensure proper balance of fat, protein, and starch intake in patients prescribed pancreatic enzyme therapy?

Answer 27

helps avoid indigestion

Question 28

Why should Weight intake be monitored in patients receiving pancreatic enzyme therapy?

Answer 28

to assess nutritional outcome

Question 29

Why should Fluid intake be monitored in patients receiving pancreatic enzyme therapy?

Answer 29

to assess nutritional outcome

Question 30

Why should Urine output be monitored in patients receiving pancreatic enzyme therapy?

Answer 30

to assess nutritional outcome

Question 31

Why should Laboratory studies be monitored in patients receiving pancreatic enzyme therapy?

Answer 31

to assess nutritional outcome

Question 32

What food affects when pancreatic enzymes should be administered?

Answer 32

Dairy products

Question 33

When should pancreatic enzymes be administered if patient will be eating dairy products?

Answer 33

15 min prior to meal

Question 34

When should pancreatic enzymes be administered if patient will be eating dairy products?

Answer 34

15 min prior to meal

Question 35

What administration option is available for infants taking pancreatic enzymes?

Answer 35

Powdered form

Question 36

How should powdered pancreatic enzymes be administered to infants?

Answer 36

mixed in applesauce

Question 37

What administration option is available for older children taking pancreatic enzymes?

Answer 37

Capsules

Question 38

How can capsules of pancreatic enzymes be administered to infants?

Answer 38

whole or sprinkled on food

Question 39

What medications should be avoided when taking pancreatic enzymes?

Answer 39

1. Strong pain medications | 2. Sedatives

Question 40

Why should strong pain medications and sedatives be avoided with pancreatic enzyme therapy?

Answer 40

1. May cause drowsiness | 2. Which will deter eating and drinking

Question 41

What non pharmacological therapy is recommended for patients undergoing pancreatic enzyme therapy?

Answer 41

Exercise

Question 42

Why is exercise recommended for patients undergoing pancreatic enzyme therapy?

Answer 42

1. Aids indigestion | 2. Improves appetite