Endocrine: Exocrine Pancreatic Enzymes Flashcards

1
Q

What are pancreatic enzymes taken for?

A

To replace missing or deficient normal pancreatic enzymes.

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2
Q

What do pancreatic enzymes do to the body?

A

Effect duodenum and upper jejunum

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3
Q

What are the pancreatic enzymes?

A
  1. Trypsin
  2. Amylase
  3. Lipase to digest
    fats.
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4
Q

What is the effect of enzymes on the duodenum and upper jejunum? Digestion

A

Digestion

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5
Q

What does Trypsin digest?

A

Proteins

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6
Q

What does Amylase digest?

A

Carbohydrates

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7
Q

What does Lipase digest?

A

Fats

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8
Q

What conditions are pancreatic enzymes indicated?

A
  1. Pancreatitis
  2. Pancreatic cancer
  3. Cystic fibrosis
  4. Following gastric resection/bypass.
  5. Steatorrhea
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9
Q

What is Steatorrhea ?

A
  1. A disorder of fat metabolism

2. Characterized by fatty, foul-smelling stools

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10
Q

When should pancreatic enzymes be administered?

A

Before meals

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11
Q

Why should pancreatic enzymes be administered before meals?

A

Ensures that the drug is available in the small intestine to help digestion

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12
Q

What drugs do pancreatic enzymes interact with?

A
  1. Antacids
  2. Calcium supplements
  3. Magnesium supplements
  4. Dairy products
  5. Folic acid
  6. Iron
  7. Acarbose
  8. Miglitol
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13
Q

What is the result of taking pancreatic enzymes with Antacids?

A

reduces effects of pancreatic enzymes

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14
Q

What is the action taken when considering administering pancreatic enzymes with Antacids?

A

Don’t give together

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15
Q

What is the result of taking pancreatic enzymes with Calcium supplements?

A

reduces effects of pancreatic enzymes

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16
Q

What is the action taken when considering administering pancreatic enzymes with Calcium supplements?

A

Don’t give together

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17
Q

What is the result of taking pancreatic enzymes with Magnesium supplements?

A

reduces effects of pancreatic enzymes

18
Q

What is the action taken when considering administering pancreatic enzymes with Magnesium supplements?

A

Don’t give together

19
Q

What is the result of taking pancreatic enzymes with folic acid?

A

Decreased absorption of folic acid

20
Q

What is the result of taking pancreatic enzymes with iron?

A

Decreased absorption of iron

21
Q

What is the result of taking pancreatic enzymes with Acarbose?

A

Reduced effectiveness of Acarbose

22
Q

What is the result of taking pancreatic enzymes with Miglitol?

A

Reduced effectiveness of Miglitol

23
Q

What are adverse reactions to pancreatic enzymes?

A
  1. Diarrhea
    2, Nausea
  2. Abdominal cramping
24
Q

What should be monitored in patients receiving pancreatic enzyme therapy?

A
  1. Bowel Movements
  2. Diet
  3. Weight
  4. Fluid intake
  5. Urine output
  6. Laboratory studies
25
Q

Why should bowel movements be monitored in patients receiving pancreatic enzyme therapy?

A

A decrease in the number of bowel movements and

improved stool consistency indicate effective therapy.

26
Q

Why should diet be monitored in patients receiving pancreatic enzyme therapy?

A

to ensure a proper balance of fat, protein,

and starch intake

27
Q

Why is it important to ensure proper balance of fat, protein, and starch intake in patients prescribed pancreatic enzyme therapy?

A

helps avoid indigestion

28
Q

Why should Weight intake be monitored in patients receiving pancreatic enzyme therapy?

A

to assess nutritional outcome

29
Q

Why should Fluid intake be monitored in patients receiving pancreatic enzyme therapy?

A

to assess nutritional outcome

30
Q

Why should Urine output be monitored in patients receiving pancreatic enzyme therapy?

A

to assess nutritional outcome

31
Q

Why should Laboratory studies be monitored in patients receiving pancreatic enzyme therapy?

A

to assess nutritional outcome

32
Q

What food affects when pancreatic enzymes should be administered?

A

Dairy products

33
Q

When should pancreatic enzymes be administered if patient will be eating dairy products?

A

15 min prior to meal

34
Q

When should pancreatic enzymes be administered if patient will be eating dairy products?

A

15 min prior to meal

35
Q

What administration option is available for infants taking pancreatic enzymes?

A

Powdered form

36
Q

How should powdered pancreatic enzymes be administered to infants?

A

mixed in applesauce

37
Q

What administration option is available for older children taking pancreatic enzymes?

A

Capsules

38
Q

How can capsules of pancreatic enzymes be administered to infants?

A

whole or sprinkled on food

39
Q

What medications should be avoided when taking pancreatic enzymes?

A
  1. Strong pain medications

2. Sedatives

40
Q

Why should strong pain medications and sedatives be avoided with pancreatic enzyme therapy?

A
  1. May cause drowsiness

2. Which will deter eating and drinking

41
Q

What non pharmacological therapy is recommended for patients undergoing pancreatic enzyme therapy?

A

Exercise

42
Q

Why is exercise recommended for patients undergoing pancreatic enzyme therapy?

A
  1. Aids indigestion

2. Improves appetite