Endocrine Exam 1 Study Guide Flashcards

1
Q

myxedema

A

Advanced Hypothyroidism

S/S:

  • depressed respirations (hypoxia, hypercapnia)
  • decreased cardiac output
  • cerebral hypoxia
  • lethargy, stupor, coma
  • hypothermia
  • bradycardia, hypotension
  • hyponatremia
  • edema that is mutinous, rather than water

TX:
synthetic thyroid replacements

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2
Q

myxedema coma

A

long term untreated hypothyroidism. life-threatening condition that occurs when hypothyroidism is untreated or when a stressor (such as an infection, heart failure, stroke, or surgery), affects an individual who hs hypothyroidism.

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3
Q

diabetes insipidus

A

a disease that results from underproduction of ADH

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4
Q

SIADH

A

The syndrome of inappropriate antidiuretic hormone (SIADH) involves the excessive secretion of ADH. Clients with SIADH cannot excrete dilute urine. Fluid retention and ultimately water intoxication occur, along with sodium deficiency. SIADH can result from central nervous system (CNS) disorders, chemotherapy, ADH production by some cancers, and overuse of vasopressin therapy.

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5
Q

graves disease

A

An immune system disorder of the butterfly-shaped gland in the throat (thyroid).

The thyroid overproduces hormones. The condition is more common in women under age 40.
Symptoms include anxiety, hand tremor, heat sensitivity, weight loss, puffy eyes and enlarged thyroid.
Treatment includes medications. Sometimes the thyroid is removed.

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6
Q

cushing’s disease

A

caused by an oversecrsetion of the adrenal cortex

A condition that occurs from exposure to high cortisol levels for a long time.

weight gain in midsection, small peripherals

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7
Q

cushion’s syndrome

A

(hyperadrenalism) results from overproduction of hormones secreted by the adrenal cortex. It can also result from overuse of corticosteroids or tumors of the adrenal glands or the pituitary.

Fat distribution is abnormal. The face is rounded (“moon face”), the abdomen is heavy and hangs down, and the arms and legs are thin. There is a noted fat pad in the neck and supraclavicular area sometimes referred to as a “buffalo hump.”

hypokalemia present

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8
Q

pheochromocytoma

A

a tumor, usually benign, that originates in the adrenal medulla. A tumor of the adrenal medulla increases secretion of the hormones epinephrine and norepinephrine, which in turn causes extreme hypertension, tremor, headache, nausea and vomiting, dizziness, and increased urination. Treatment is surgical removal of the tumor—a dangerous operation because it may cause sudden and extreme changes in blood pressure.

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9
Q

thyroid storm/crisis

A

Thyroid storm is a life-threatening health condition that is associated with untreated or undertreated hyperthyroidism. During thyroid storm, an individual’s heart rate, blood pressure, and body temperature can soar to dangerously high levels. Without prompt, aggressive treatment, thyroid storm is often fatal.

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10
Q

hashimotos thyroiditis

A

is hypothyroidism believed to be autoimmune in origin. It is of the type of autoimmune disorders known as organ specific because the body builds up antibodies against thyroid tissue only.

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11
Q

tetany

A

a generalized continuous muscle spasm of the entire body. It is most often caused by accidental removal of the parathyroid glands during thyroidectomy.
Chvostek’s sign (abnormal spasm of the facial muscles in response to light taps on the facial nerve) and Trousseau’s sign (wrist spasm with BP cuff)

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12
Q

goiters

A

enlarged thyroid gland, but no symptoms of T4 deficiency are there.

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13
Q

Addison’s disease

A

A disorder in which the adrenal glands don’t produce enough hormones.

Specifically, the adrenal glands produce insufficient amounts of the hormone cortisol and sometimes aldosterone, too. When the body is under stress (e.g. fighting an infection), this deficiency of cortisol can result in a life threatening Addisonian crisis characterized by low blood pressure.
Symptoms tend to be non-specific and include fatigue, nausea, darkening of the skin, and dizziness upon standing.
Treatment involves taking hormones to replace those not produced by the adrenal glands.

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14
Q

addisonian crisis

A

serious medical emergency caused by extremely low levels of cortisol. Cortisol is an important hormone produced by the adrenal glands and is normally released as part of the body’s response to stress. People with Addison’s disease are at the greatest risk of developing an Addisonian crisis

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15
Q

acromegaly

A

A disorder in adults in which the pituitary gland produces too much growth hormone.

Acromegaly is usually caused by a noncancerous tumor. Middle-aged adults are most commonly affected.
Symptoms include enlargement of the face, hands, and feet.
Prompt treatment is needed to avoid serious illness. Drugs can reduce the effects of growth hormone. If needed, surgery and radiation may be used to remove tumor cells.

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16
Q

kidney stones

A

A small, hard deposit that forms in the kidneys and is often painful when passed.

The most common symptom is severe pain, usually in the side of the abdomen, that’s often associated with nausea.
Treatment includes pain relievers and drinking lots of water to help pass the stone. Medical procedures may be needed to remove or break up larger stones.

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17
Q

hyperthryroidism

A

clinical syndrome caused by excessive circulating thyroid hormone. Thyroid hormone exaggerates normal body functions and produces a hyper metabolic state and increased sympathetic nervous system

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18
Q

hypothyroidism

A

condition in which there is an inadequate amount of circulating thyroid hormones T3 and T4 causing a decrease in metabolic rate that affects all body systems

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19
Q

hyperparathyroidism

A

stems from an excess of PTH that causes blood calcium levels to rise, resulting in calcium depletion in bones (osteomalacia). Bones become soft and weak, leading to skeletal tenderness. They tend to break easily.

The skull may enlarge. Muscles weaken, and the client complains of fatigue, nausea, and constipation. Kidney stones, urinary tract infections, and uremia may develop. The person may become disoriented and paranoid and may lose consciousness. This condition may be secondary to chronic nephritis.

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20
Q

hypoparathyroidism

A

the deficiency of PTH, results from lowered production of the hormone, with a consequent reduction in the amount of calcium available to the body and an accumulation of phosphorus in the blood. Accidental removal of the parathyroid glands during a thyroidectomy may cause hypoparathyroidism.

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21
Q

hypercortisolism

A

aka cushing syndrome

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22
Q

acute adrenal insufficiency

A

also known as an acute adrenal crisis.

People who have a condition called Addison’s disease or who have damaged adrenal glands may not be able to produce enough cortisol. Low levels of cortisol can cause weakness, fatigue, and low blood pressure.

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23
Q

pituitary adenoma

A

Noncancerous tumors in the pituitary gland that don’t spread beyond the skull.

The pituitary gland is in the skull, below the brain and above the nasal passages. A large tumor can press upon and damage the brain and nerves.
Vision changes or headaches are symptoms. In some cases, hormones can also be affected, interfering with menstrual cycles and causing sexual dysfunction.
Treatments include surgery and medications to block excess hormone production or shrink the tumor. In some cases, radiation may also be used.

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24
Q

normal ranges for adult
VS
Blood Sugar

A

Temp: 96.8 - 101.3
Pulse: 60 - 100 BPM
Resp: 12 - 20 RPM
BP: 90/60 ,<120/<80, 139/89

Blood Sugar: 70 - 110 ATI

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25
Q

vasopressin (pitressin)

A

TREATS DIABETES INSIPIDUS

26
Q

demeclocycline (declomycin)

A

TREAT SIADH

monitor I and O

27
Q

levothyroxine (synthroid)

A

HYPOTHYROIDISM
thyroid hormone replacement therapy
– increases effects of warfarin and increases need for insulin and digoxin
– meds that decrease levothyroxine - cimetidine, lasoprazole, and colestipol

  • use caution with older clients and those who have CAD to avoid coronary ischemia. start with low doses
  • monitor cardiovascular compromise
  • tx begins slowly and is increased every 2-3 weeks until desired response is obtained
  • serum TSH is monitored
  • take on an empty stomach 1-2 hours before
    eating
  • fiber supplements, calcium, iron, and antacids interfere with absorption
28
Q

spironolactone (aldactone)

A

TREATS CUSHSINGS DISEASE/SYNDROME

  • Aldosterone antagonist
  • Potassium-sparing diuretic
  • Used when bilateral adrenal hyperplasia is the underlying case

Monitor electrolytes (sodium and potassium), vital signs and weight

  • take with food to promote absorption
  • restrict high potassium intake
  • use NO salt substitutes
  • report indications of hyperkalemia
  • report menstrual changes
29
Q

prednisone (deltasone)

A

TREATS ADDISONS DISEASE

adrenocorticoid replacement for adrenal insufficiency

  • monitor weight, BP, and electrolytes
  • increase dosage during periods of stress or illness
  • tape if d/c’ing
  • take with food
  • take as directed
  • report symptoms of cushing’s syndrome (round face, edema, weight gain)
  • report symptoms (fever, fatigue, muscle weakness, anorexia)
30
Q

calcium chloride (IV route)

A

TREATS HYPOPARATHYROIDISM

calcium supplemento

31
Q

calcitonin

A

TREATS HYPERPARATHYROIDISM
Calcitonin is a hormone that the C-cells in the thyroid gland produce and release. It opposes the action of the parathyroid hormone, helping to regulate the blood’s calcium and phosphate levels.

32
Q

insulin

A

.

33
Q

aminoglutethmide (cytadren)

A

TREATS CUSHSINGS DISEASE/SYNDROME
adrenal corticosteroid inhibitor
decreases adrenal hormone synthesis to provide short term symptom relief

  • use temporarily until surgery or other treatment is finished, no longer than 3 months
  • monitor BP for hypotension
  • monitor fluids and electrolytes
  • advise client to not drive heavy machinery
  • causes N/V, drowsiness, rash
  • relief is temporary
  • take with food for GI upset
34
Q

mitotane (lysodren)

A

TREATS CUSHSINGS DISEASE/SYNDROME
suppresses action of adrenal cortex

treats inoperable adrenal carcinoma
monitor for indications of shock and hepatotoxicity

  • advise that it’s purpose is to decrease the size of the tumor
  • notify provider of weakness, dizziness, N/V, and weight loss
  • use caution when driving or operating heavy machinery
35
Q

ketoconazole

A

TREATS CUSHSINGS DISEASE/SYNDROME

  • adrenal corticosteroid inhibitor
  • an anti fungal agent that inhibits adrenal corticosteroid synthesis when taking in high dosages
  • can be used in addition to radiation or surgery
  • monitor liver enzymes and indications of liver toxicity (yellow sclera, dark urine)
  • monitor fluid and electrolytes for clients with gastric effects
  • medication can cause N/V
  • relief is temporary. if meds are d/c’d, symptoms will return
  • take with food
36
Q

hydrocortisone (cortef)

prednisone and cortisone

A

TREATS ADDISONS DISEASE

adrenocorticoid replacement for adrenal insufficiency

  • monitor weight, BP, and electrolytes
  • increase dosage during periods of stress or illness
  • tape if d/c’ing
  • take with food
  • take as directed
  • report symptoms of cushing’s syndrome (round face, edema, weight gain)
  • report symptoms (fever, fatigue, muscle weakness, anorexia)
37
Q

liothyronine (cytomel)

A

TREATS HYPOTHYRODISM/ EMERGENCY TREATMENT OF MYXEDEMA COMA

38
Q

propranolol (inderal)

A

HYPERTHYROIDISM
beta-adrenergic blocker
treats sympathetic nervous system effects (tachycardia, palpitations)

  • monitor BP, HR, and ECG
  • monitor hypoglycemia
  • medication can cause dizziness and to sit before standing
  • teach client to check pulse before dose
  • d/c only when provider says so
39
Q

iodine (lugol’s solution)

A

HYPERTHYROIDISM
Lugol’s solution and saturated solution of potassium iodine (SSKI) inhibit release of thyroid hormone

  • for short term use only
  • administer 1 hour after antithyroid meds
  • contraindicated in pregnancy
  • notify provider of fever, sore throat, and mouth ulcers
  • available as a solution. mix with juice/liquid
40
Q

what is the most appropriate action for the nurse to do during her assessment is to document any abnormalities

A

document any abnormalities. Just in case anything changes, she can prove things got worse or better with every entry.

41
Q

what is the directions you will teach your patient who is going to have a “cortisol 24 hour urine test” in order to have an accurate test

A
  • Instruct client that high levels indicate hypercortisolism
  • Client empties his bladder and then collects all urine excreted during the next 24- hour period
  • The urine must be kept in a jug with boric acid added and kept on ice
  • If the client is receiving spironolactone, this should be withheld for 7 days prior to the test
42
Q

what is the “water deprivation test” about and what are you assessing DURING the testa and WHY

A

A fluid or water deprivation test is a medical test which can be used to determine whether the patient has diabetes insipidus as opposed to other causes of polydipsia (a condition of excessive thirst that causes an excessive intake of water).

43
Q

what does photophobia have to do with thyroid replacement therapy

A

hypothyroidism and is prescribed a synthetic hormone replacement. too high of a dosage causes photophobia

44
Q

what is the VMA (vanillymandelic acid) test about, along with tx to ensure an accurate test

A
  • Caffeine, vanilla, bananas and chocolate might be restricted for 2-3 days before the test
  • Clients may be asked to withhold aspirin and antiHTN meds
  • Instruct the client to maintain a moderate level of activity, avoiding vigorous exercise or stress
45
Q

what is the phentolamine blocking test?

A

A rapid decrease in systolic BP or greater than or equal to 35 and diastolic BP of greater than or equal to 25 with the administration of phentolamine is diagnostic for pheochromocytoma.

46
Q

what are the side effects of long term steroid use

A

increased appetite, fluid retention, weight gain, increased blood sugar (which can lead to diabetes), change in body shape (increase in fatty tissue on the trunk while the arms and legs get thinner), increased susceptibility to infections, acne, thinning of the skin, easy bruising

47
Q

what pt information you will ask PRIOR to their CT scan with contrast, why

A

allergies

48
Q

what is a transsphenoidal hypophysectomy resection

A

Surgical removal of the pituitary gland. Priority monitoring

49
Q

what is the immediate post op care for the pt that just had a transsphenoidal hyphysectomy

A
  • Monitor and correct electrolytes, especially Na, K and Cl
  • Monitor and adjust serum glucose levels
  • Monitor ECG
  • Protect client from infection by performing hand hygiene and avoiding contact with individuals who have infection.
  • Implement fall precautions
  • Monitor for bleeding
  • Monitor nasal drainage for a possible CSF leak
  • Inspect drainage for presence of glucose or a halo sign (yellow on the edge and clear in the middle), which can indicate CSF
  • Document neurologic condition every hour for the first 24 hours and then every 4 hours.
  • Administer glucocorticoids to prevent abrupt drop in cortisol level
  • Administer stool softeners as ordered to prevent straining
50
Q

what is an adrenalectomy

A

surgical removal of the adrenal gland (can be unilateral or bilateral)

removal of both is avoided if possible because the client will require lifelong replacement therapy

51
Q

what is follicle-stimulating hormone (FSH) stimulating

A

In women, FSH helps control the menstrual cycle and the production of eggs by the ovaries.

52
Q

erythropoietin is related from what organ and why

A

by the kidney that leads to the formation of red blood cells in the bone marrow.

53
Q

what is insulin and glucoses relationship

A

Insulin and glucagon are hormones secreted by islet cells within the pancreas. They are both secreted in response to blood sugar levels, but in opposite fashion! Insulin is normally secreted by the beta cells (a type of islet cell) of the pancreas

54
Q

what does positive chvostek’s sign have to do with a throidectomy

A

A positive response varies from twitching of the lip at the corner of the mouth to spasm of all facial muscles, depending on the severity of hypocalcemia- the disease it is associated with.

55
Q

parathyroid hormones relationship to calcium is what

A

The four parathyroid glands make more or less parathyroid hormone (PTH) in response to the level of calcium in the blood. When the calcium in our blood goes too low, the parathyroid glands make more PTH. Increased PTH causes the body to put more calcium into the blood.

56
Q

what is the fx of glucocorticoids in the body

A

steroids that reduce inflammation throughout the body. Cortisol is a naturally occurring GC that is made by your adrenal glands, and works to regulate inflammation and other processes in your body.

57
Q

production and release of vasopression causes the kidneys to do what and why

A

causes the kidneys to retain water

58
Q

what does endogenous mean

A

growing or originating from within an organism.

59
Q

what is the immediate thyroidectomy its post op care fro the next 24 hours you will focus on and why

A

airway

60
Q

IMMEDIATE post op care for the adrenalectomy pt and why

A

monitor for adrenal crisis due to an abrupt drop in cortisol level. Findings can include:

  • hypotension
  • tachycardia
  • tachypnea
  • nausea
  • headache
  • Monitor VS and hemodynamic levels frequently (every 15 min initially).
  • Monitor fluid and electrolytes
  • Monitor the incision site for bleeding
  • Monitor bowel sounds
  • Provide pain meds and stool softeners as needed
  • Slowly introduce foods
  • Check abd. For distention and tenderness. Monitor incision site for redness, discharge and swelling.
  • Reinforce pt. teaching about post op pain management, deep breathing and anti- embolism care.
  • Advise the client of the ned to take glucocorticoids, mineralcorticoids and hormone replacements.
61
Q

reporting nausea and projectile vomiting to your provider is important why with a brain tumor patient

A

we can give meds to stop the nauseousness with drugs so pressure doesn’t get placed in the head while vomiting. prevents further injury.