endocrine embryology

Question 1

where does each of the following derive
pituitary - adeno and neuro
pineal
thyroid
parathyroid
adrenal

Answer 1

pituitary adeno from roof of mouth
pituitary neuro from hypothalamus
pineal - from CNS
thyroid from floor of mouth
parathyroids - pharyngeal arches
adrenal - medulla from neuroectoderm and cortex from mesoderm

Question 2

embryology of the pituitary what defect is this related to

Answer 2

-upgrowth of ectoderm of the roof of the developing mouth creating rathkes pouch
-this cups around the developing neurohypophysis
-connection to the mouth is lost
pituitary dwarfism - occurs if rathkes pouch doesn’t differentiate into glandular tissue
-the neurophysis is a downgrowth of the ectoderm of the forebrain

Question 3

in the thyroid where do the follicular and c cells derive from ?

Answer 3

follicular cells are from the downgrowth of the pharyngeal endoderm of the developign tongue
c cells from the ultimobracheal - most caudal pharyngeal pouch