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Year 3 - Pharmacology > Endocrine drugs > Flashcards

Endocrine drugs Flashcards

1
Q

what is the main drug used to treat hyperthyroidism? what is its MOA?

A

CARBIMAZOLE: inhibits thyroid peroxidase from coupling and iodinating tyrosine residues on thyroglobulin - reduces thyroid hormone production.

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2
Q

main ADRs of carbimazole?

A
  1. Agranulocytosis - advise pt to seek medical advice if sore throat, mouth ulcers, bruising, fever, malaise…
  2. Crosses placental barrier - but may still be used at low dose in pregnancy if benefits > risks
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Year 3 - Pharmacology (11 decks)

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