ENDOCRINE DRUGS Flashcards
Peptide hormones cannot be taken orally because
of the proteolytic enzymes present in Gastrointestinal Tract
What contraindications of somatrem [protropin] and somatropin [humantrope] growth hormones have?
Contraindicates on patient who has hypersensitivity and closed epiphyses
What are the adverse effects of taking growth hormones?
antibody formation, lipoatrophy, diabetogenic, local irritation at the injection site, and fluid retention.
What medicine is a growth hormone-inhibiting hormone contraindicated to hypersensitivity, pregnancy, and lactation?
Ocreotide [sandostatin], somatostatin, and lanreotide
What are the adverse effects of taking somatostatin agonists?
gastrointestinal distress, constipation or diarrhea, flatulence, nausea, acute cholecystitis
ADH [Vasopressin], pitressin synthetic, and desmopressin are indicated to
Diabetes Insidipus [IV, Nasal], hemorrhage, and postoperative abdominal distention
What are the two adverse effects of taking ADH [Vasopressin], pitressin synthetic, and desmopressin?
Water intoxication and hangover effect
It is used to initiate labor, promote delivery to the placenta, and control post-partum hemorrhage, as well as promote breastmilk let-down. It is?
Oxytocin
What are the adverse effects of taking oxytocin?
Hypersensitivity, cardiovascular spasm, hypotension and nausea, and vomiting
Norepinephrine and epinephrine released by
Adrenal medulla
What hormones are released by the adrenal cortex?
Corticosteroids
What are Corticosteroids?
androgens, glucocorticosteroids, and mineralocorticoids
Glucocorticoids increase the availability of glucose but also a?
anti-inflammatory and immuno suppressant
What glucocorticoid is preferred for adrenocortical insufficiency?
Hydrocortisone
What glucocorticoid is used as an oral therapy for chronic adrenal insufficiency?
Cortisone
