Endocrine Drugs Flashcards
What is Hormones?
A chemical substance produced in the body that controls and regulates
the activity of certain cells or organs
Peptide
Cannot be given orally because of proteolytic enzymes in the GIT
Steroid
Effective when injected
Growth Hormone
Stimulates growth in tissue and bone
Adverse Effects of Growth hormone
antibody formation, lipoatrophy, diabetogenic, local irritation at
injection site, fluid retention
Somatostatin Agonist
Growth hormone inhibiting hormone [GHIH]
Gliptins
Increases insulin release, reduces glucagon release
Thiazolidinediones
Decrease insulin resistance, increase glucose uptake and decrease glucose production in liver
Alpha-Glucosidae Inhibitors
Reduces rate starches are broken down and absorbed; decreases post-prandial rise in blood
glucose
Pancreas
Release insulin and glucagon from the Islets of Langerhans
Diabetes Mellitus
a group of metabolic disorders of fat, carbohydrate, and protein metabolism that results from defects in insulin secretion, insulin action (sensitivity), or both
Adrenal Medulla
Releases neurotransmitters Norepinephrine and Epinephrine
Adrenal Cortex
Produces hormones called CORTICOSTERIODS
What is Oxytocin?
Used to initiate labor, promote delivery of placenta and control post-partum hemorrhage
Adverse Effects of Oxytocin
hypersensitivity, cardiovascular spasm, hypotension, N&V