Endocrine control Flashcards

0
Q

Exocrine Gland

A

-contains a duct

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1
Q

Endocrine Gland

A
  • ductless gland

- makes hormones secreted directly into bloodstream

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2
Q

Paracrine

A
  • hormone acting in localized region

- affects a target cell nearby the secreting cell

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3
Q

Non-Steroid Hormone

A
  • binds to cell surface receptor
  • binding causes conformational change of receptor
  • causes cascade of chemical rxns
  • very specific
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4
Q

Steroid Hormone

A
  • could cross cell membrane
  • receptors can be in cytoplasm or nucleus
  • cytoplasmic receptor binds to hormone and is moved into nucleus
  • turn on genes–>make proteins
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5
Q

Prolactin

A
  • secreted by anterior pit

- causes production of milk

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6
Q

FSH

A
  • in women, stimulates maturation of the follicle

- in men, stimulates sperm production

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7
Q

LH

A
  • in women, its the trigger for ovulation

- in men, it stimulates testosterone production

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8
Q

Kisspeptin Neurons

A

-have receptors that will relay negative feedback message to GnRH neurons

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9
Q

Kallman Syndrome

A
  • primary symptom is failure to start puberty, infertility
  • GnRH neurons fail to migrate into hypothalamus during embryonic development
  • inability to smell
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10
Q

SRY Region

A
  • sex determining region

- responsible for production of testes determining factor(TDF)

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11
Q

TDF

A

-causes formation of testes

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12
Q

Anti-Mullarian Hormone(AMH)

A
  • produced by Sertoli cells of the testes

- kills off mullarian ducts

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13
Q

5(alpha)-Reductase

A
  • enzyme produced in Sertoli cells of testes
  • converts testosterone into dihydrotestosterone(DHT)
  • necessary for development of external male structures
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14
Q

Testicular Feminization

A
  • receptors for testosterone absent in wolfian ducts
  • externally female, internally male
  • neither wolfian nor Müllerian ducts survive
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15
Q

Gueveduces

A
  • mutation in 5(alpha)-Reductase
  • testosterone not converted into DHT
  • externally female at birth, puberty causes individuals to masculinize
16
Q

Adrenogenital syndrome (xx)

A
  • adrenal gland can’t make cortisol, instead makes large amounts of androgens–>masculinized the female body
  • in males, this would cause precocious sexual development
17
Q

Precocious Puberty

A
  • expressed only in males even if females have genotype
  • males with autosomal dominant allele undergo puberty early
  • receptor of LH mutated to always “on” state
18
Q

Wolfian ducts

A

-become epididymis, vas deferens, and penis shaft

19
Q

Müllerian ducts

A

become uterus, Fallopian tubes, cervix, and upper vagina