endocrine and reproductive Flashcards
what are the functions of the endocrine system
maintain homeostasis by regulating metabolic processes
endocrine glands
release into internal environment (via bloodstream)
exocrine glands
release into external environment (skin)
paracrine glands
release into neighboring cells
autocrine glands
release into self
NS -> ES cell
neuron, epithelial and others
NS -> ES chemical signal
neurotransmitter, hormone
NS -> ES specificity of response
postsynaptic cell, target cell
steroid hormones
testosterone, estrogen, aldosterone, cortisol
nonsteroid hormones
norepinephrine, epinephrine, thyroxine, ADH, GH, oxytocin, prolactin, PTH, LH , FSH, TSH
Which type of hormone is soluble in water?
nonsteroid
Which hormone is made of complex C, H rings with some oxygen atoms?
steroid
What are prostaglandins?
Hormone-like chemical signals, made of lipids. Very potent.
Hypothalamus/Anterior Pituitary gland
Hypothalamus -> anterior pituitary -> peripheral endocrine gland -> target cell -> action
Hypothalamus/Anterior Pituitary gland
Releasing hormones (TRH, GnRH, GRH, CRH)
Nervous System
Nervous System -> endocrine gland -> target cells -> action
Nervous System
Stimulates gland directly (adrenal medulla, epinephrine/norepinephrine)
Response to change in plasma
Changing level of substance in plasma -> endocrine gland -> target cells -> action
Response to change in plasma
Pancreas (blood sugar levels)
anterior pituitary hormones
growth hormone, prolactin, thyroid-stimulating hormone, adrenocorticotropic hormone, follicle-stimulating hormone, luteinizing hormone
growth hormone
increase size and division rate of cells
prolactin
post-birth milk production
thyroid-stimulating hormone
stimulates hormones secreted by the thyroid gland
adrenocorticotropic hormone
stimulates hormones secreted by adrenal cortex
follicle-stimulating hormone
males: sperm cell production
females: development of egg-containing follicles, secrete estrogen
luteinizing hormone
stimulates sex hormone secretion, plays a role in ovulation (menstural cycle)
antidiuretic hormone
causes kidneys to conserve water. can constrict blood vessels
oxytocin
contracts smooth muscle in uterine wall, contracts myoepithelial cells associated with milk-secreting glands
What is the gland located inferior to the larynx by Adam’s apple
Thyroid gland
What hormones are secreted by the thyroid?
Thyroxine (T4), Triiodothyronine (T3), calcitonin
what is the function of T4
increases basal metabolic rate, increases growth
what is the function of T3
more potent than T4
what is the function of calcitonin
lowers calcium in blood, stimulates osteoblasts
how is the secretion of T3 and T4 regulated?
hypothalamus/anterior pituitary
how is the secretion of calcitonin regulated?
response to changes in plasma
where are the parathyroid glands located?
posterior surface of thyroid
what hormone is secreted by the parathyroid?
Parathyroid hormone
what is the function of PTH
increase levels of calcium in blood, causes kidneys to conserve more Ca and activates vitamin D
where are the adrenal glands?
superior to the kidney. Cortex is superficial, medulla is deep
what hormones are released by the medulla?
epinephrine and norepinephrine
what is the function of epinephrine and norepinephrine?
adrenaline, increases heart rate, dilates airways, fight or flight response
how is the medulla regulated?
nervous system
what hormones are released by the cortex?
aldosterone, cortisol, adrenal sex hormones
what is the function of aldosterone?
regulate electrolytes in body, sodium vs. potassium levels
what is the function of cortisol?
body’s response to stress
what is the function of adrenal sex hormones
supplement sex hormones from the gonads
how is aldosterone regulated?
response to changes in plasma
how is cortisol regulated?
hypothalamus/anterior pituitary gland
where is the pancreas located?
posterior to stomach, chewed up gum
what hormones are released by the pancreas?
glucagon, insulin
what is the function of glucagon?
increase blood sugar (released by alpha cells)
what is the function of insulin?
decrease blood sugar (released by beta cells)
how are the hormones of the pancreas regulated?
response to changes in plasma
where is the pineal gland located?
upper part of the thalamus
what hormone is released by the pineal gland?
melatonin
what is the function of melatonin?
sleep-wake cycle
where is the thymus?
posterior to sternum
what hormones are released by the thymus?
thymosins
what is the function of thymosins?
affect production and differentiation of white blood cells, t cells
where is the placenta?
surround fetus during pregnancy
what hormones are released by the placenta?
estrogens, progesterone, and gonadotropins
what hormones are released by the placenta?
estrogens, progesterone, and gonadotropins
what is the male sex cell?
sperm
what is the female sex cell?
oocyte
What is the structure of the testes?
contain many lobules with contain seminiferous tubules which lead to the epididymis
What is the function of the interstitial cells of the male reproductive system?
produce and secrete male sex hormone
what is the epididymis?
tightly coiled tube within testicle, holds sperm
what is the passage of the vas defernes?
passes through medial side of testis through lower abdominal wall, enters pelvic cavity. combines with ejaculatory duct to pass through urethra
what is the function of secretions of the seminal vesicles?
rich in fructose and nutrients for sperm
where is the prostate gland?
below the bladder in front of the rectum
what triggers the changes of puberty?
hyporthalamus secretes GnRH
what are primordial follicles?
first class of ovarian follicles formed.
how is oogenesis different from spermatogenesis?
4 gametes are viable for sperm but only 1 for females
what triggers ovulation?
Release of LH by anterior pituitary
what are the sources of female sex hormones?
ovaries, adrenal cortex, placenta
what is the function of estrogen?
stimulate rep. organ development, secondary sex characteristics
what is the function of progesterone?
changes in uterus during menstural cycles
what is the function of androgens in females?
puberty changes, hair growth