Endocrine and GI Flashcards

0
Q

What can stimulate the liver to produce more glucose?

A

Increase hormone production

Cortisol

Glucagon

Epinephrine

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1
Q

Number 1 cause of dka

A

Infection

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2
Q

What meds put u at risk for hhs?

A
Glucocorticoid 
Diuretics
Phenytoin (Dilantin)
Propranolol
Calcium channel blockers
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3
Q

Med conditions that put u at risk for hhs

A

Mi
Cerebral vascular injury
Sepsis

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4
Q

Which will cause myoclonus jerking, seizures, and reversible paralysis? DKA OR HHS

A

HHA

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5
Q

DKA GLucose

A

⬆️300

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6
Q

HHS glucose

A

⬆️600

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7
Q

HHS

A

Osmolarity ⬆️320

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8
Q

Monitor glucose every hour

What is goal glucose?

A

⬇️200

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9
Q

Correcting acidosis too fast can do what to k

A

Hypok

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10
Q

How often should old people check glucose when sick?

A

1-4 hrs

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11
Q

Hhs osmolarity

A

Above 320

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12
Q

Notify provider if glucose is above

A

240

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13
Q

Severe acidotic state

A

PH less than 7.15

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14
Q

What kind of fluid replacement is the gold?

A

To replace half the estimated fluid deficit over the first eight hours

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15
Q

The second half of fluid replacement is given over how many hours

A

The next 16 hours that way within the first 24 hours of treatment fluid deficit should be corrected

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16
Q

What is the order of fluids given in DKA and HHS?

A
  1. 9% normal saline
  2. 45% normal saline

5% dextrose (when glucose becomes 200 to prevent hypoglycemia and resolve ketosis)

17
Q

What should potassium be before insulin administration?

A

At least 3.3

18
Q

Difference in primary and secondary adrenal insufficiency

A

Primary
#⃣ deficient in both glucocorticoids in mineralocorticoids
Secondary
#⃣deficient in glucocorticoids alone

19
Q

What is the first sign of hypoglycemia

A

Change in mental status

20
Q

Counterregulatory hormones with the sympathetic nervous system response and hypoglycemia

A

Glucagon, epinephrine, cortisol, and growth hormone

21
Q

What is the best clinical indicator of effective treatment for hypoglycemia?

A

Neurological status

22
Q

Cortisol level in adrenal crisis

A

⬇️10 mg/dL

23
Q

What is cosyntropin

A

Synthetic ACTH

24
Standard dose of cosyntropin
250 mcg (with a result of an increase in cortisol level of 7 to 9 from baseline)
25
ACTH stimulates this glucocorticoid to release
Cortisol
26
I'll dust around is a mineralocorticoid that has what effect
It's made in the adrenal Cortex and regulates the bodies electrolyte and water balance in the renal tubules
27
Adrenal crisis lab value of glucose
Less than 50
28
Adrenal crisis lab value of cortisol
Less than 10
29
Adrenal lab value of potassium
Either greater than 6.6 Or less than 3.0
30
Adrenal crisis lab value for sodium
Greater than 150 or less then 130
31
Adrenal crisis BUN value
Greater than 20
32
Adrenal crisis pH value
Less than 7.3
33
What fluid is given initially in adrenal crisis until signs and symptoms of hypovolemia stabilize?
5% dextrose and normal saline
34
The patient may need how much of this fluid in the first 12 to 24 hours of adrenal insufficiency?
As much as 5 L
35
How is hyperkalemia treated in adrenal crisis?
With fluid and glucocorticoid replacement, it may not have to be treated specifically
36
What drug can be given IV push before the cortisol test is done
``` Dexamethasone phosphate (Decadron) 4 mg every eight hours until cosyntropin test has been done ```
37
What do thyroid hormones bind to
Globulin, T4 binding pre-albumin, and albumin
38
What is the relationship between T4 and T3
95% of thyroid hormones in the body or T4,T4 converts into T3, T3 is more potent than T4
39
Peak times
Insulin