Endocrine Flashcards
Causes of solitary thyroid nodule
Cyst (commonest)
Adenoma
Dominant nodule in MNG
Carcinoma
Causes of diffuse thyroid enlargement
Graves’ disease
Thyroiditis
Physiological
Prognostic factors in thyroid cancer
"AGES" Age (worse at the extremes of age) Gender (men have worse prognosis) Extent (mets obviously bad) Size (large is bad)
Main investigations
Bloods: TFTs, thyroid autoAbs (anti-TSHR); anti-TPO.
Imaging: USS +/- FNAC and bx; CT/MRI; radio-isotope scan (in solitary nodules, only useful if the patient is thyrotoxic, and can help determine whether the nodule itself is toxic and symptomatic.
Complications of thyroid surgery
Recurrent laryngeal nerve damage - hoarse voice
Superior laryngeal nerve damage - loss of high pitch
Hypocalcaemia
Haematoma (need to decompress it)
Respiratory obstruction
Thyroid storm intra-operatively
Hypothyroidism
Complications of retro eternal goitre extensions
Tracheal shift
SVCO
Oesophageal obstruction
Tracheomalacia
Submandibular triangle lump
Lymph node
Submandibular gland (obstructed, infected, neoplasm)
Parotid tail
(Lymphangioma - like a more invasive and difficult to treat cystic hygroma)
Submental triangle lump causes
Sublingual gland enlargement (?ranula. As the gland enlarges and plunges through the myelohyoid muscle)
Lymph node
Dermoid cyst/teratoma
Carotid triangle lump causes
Carotid body tumours
Lymph nodes - JUGULODIGASTRIC LYMPH NODE
neuromas/schwannomas/neurofibromas of vagus nerve
BRANCHIAL CYST
Muscular triangle lump causes
Thyroid Thyroglossal cyst Lymph node Dermoid cyst Laryngeal masses Laryngocele (air-filled saccule, which can develop in instrument players, particularly brass players who do a lot of blowing)
Occipital triangle lump causes
Lymph node
Cystic hygroma
Supraclavicular triangle lump causes
VIRCHOW’S LYMPH NODE
- need to examine for malignancies anywhere below the clavicle - mainly CHEST, ABDO, BREAST
- also could be thyroid malignancy
Investigations in head and neck lumps
X-ray Angio (vascular lesions, eg carotid body stuff) Sialogram Nuclear imaging Others: viral serology etc.
Causes of enlarged lymph node
Infectious - local or systemic
Mets - local or systemic
Primary (lymphoma)
Miscellaneous (eg. Rheumatoid, sarcoid etc)
Rule of 80s in salivary tumours
80% in parotid
80% is adenomas
80% is pleomorphic