Endocrine

Question 1

Differentials for hyperthyroidism

Answer 1

Graves 
Toxic multinodular goitre 
Toxic adenoma
Postpartum thyroiditis 
TB (rare)
de Quervain

Question 2

Graves

Answer 2

Most common cause of hyperthyroidism
More common in females

TSH receptor antibodies

Extrathyroidal manifestations include orbitopathy, pretibial myxoedema (thyroid dermopathy), or acropachy, which do not occur with other causes of hyperthyroidism

Question 3

Toxic adenoma

Answer 3

Single large thyroid nodule showing hot area on scan + suppression of extra nodular thyroid tissue

Does not generally remit and needs definitive tx

Benign

Question 4

Toxic multinodular goitre

Answer 4

Older patients
Gradual onset and sx less dramatic than Graves

Does not generally remit so needs definitive tx

Benign

Multiple nodules