Endocrine Flashcards
oral glucose tolerance test
give 75mg glucose w/ 300ml h20 after overnight fast. >200mg/dL glucose at 2hours and 1 other time=diabetic
diabetic meds:sulfonylureas
bind b cells and stimulate insulin
ride, zide
hold day of
diabetic meds: biguanides
metformin, decrease production of glucose in liver
hold 2 days
diabetic meds:thiazolidinediones
increase peripheral cell response to insulin
-glitz
hold day of
diabetic meds:a glucosidase inhibitors
reduce intestinal CHO absorption
acarbose and miglitol
hold day of
diabetic meds: rapid
lispro and aspart 15 min onset, 2 hr peak, 5 hr duration
diabetic meds: short
regular insulin 1 hour onset, 4 hr peak 8hr duration
diabetic meds: intermediate
NPH and lente
3-4h onset, 12h peak, 20h duration
diabetic meds: long acting
glargine and detemir
1-3 h onset, no peak, 24 h duration
diabetic meds: 70/30
NPH/Regular
1 hr onset, 10 h peak, 18 h duration
cushing syn what is it? due to? dx?
excess cortisol, due to ACTH or adrenal cancer
24 h urin free cortisol >250 or 1 mg of dex the night before and it is > 50nmol/L
adisons causes? Labs? primary disease skin?
autoimmune adrenalitis, histoplasma, cocciodes,
hypoNA, hypo glycemia, hyperK,
narrow cardiac stilhouette
hyperpigmentation due to proopiomelanocortin
hypothyroidism. TSH stimulated by?
TSH inhibited by? types?
presentation in kids
stim: a adrenergic agonists
inhib: dopa, bromocreptine, somatostatin, corticosteroids
types: iodine deficient (Hashimoto)=elevated TSH low t4
2ndary: pituitiary failure or hypothalamic=low TSH and t4
kids=cretenism-short with severe mental retardation and coarse face
hypertheroidism types?triad?
1=diffuse hyperplasia
2= tsh secretining pituitary adenoma
triad=hypertyroidism, opthalmopathy and dermopathy(pretibial)
diseases associated with hyperthyroidism due to extra t3 and t4
SLE DM1
