anesthesia Flashcards
general supresses in this order
psychic-> basal ganglion/cerebellum-> medullary centers-> spinal cord
mey overton theory
more lipid=more potent
GABA=
amnesia and hyponosis
Nicotinic ach
amnesia
glycine
immobility
blood gas partition
lower=fater rate of induction
Nitrous oxide
analgesic NMDA antagonist, fast acting
-> hypoxia
halothane
anesthetic fast acting
-> arrythmia, liver toxicity hypothermia
Sevoflurane
anestetic, fast induction, less odor
-> high hepatic metabolism
PREFFERED IN ASTHMATICS
Isoflurane
relaxant
lowest MAC
-> vasodiation, bronchodilation, pungent
Desflurane
relaxant
fast induction and emergence
Indicated for pts with LIVER problems
NOT for smokers
vecuronium
ach antagonist
few CV effects
-> residual muscle weakness (tx neostigmine
NOT for renal dysfunction
Midazolam
benzo
-> oversediatation
fentanyl
opiod
-> resp depression
thiopental
Rapid/potent
-> hypotnesion,laryngospasm, grogginess
proprofol
good for asthmatics
etomidate
-> 11 B hydroxylase adrenal supression, myoclonus
NOT if history of seizures
Succinylcholine
-> fasiculations, myalgia, bradycardia, MI, hyper kalemia
Not for Malignant hyperthermia
Rimifentanyl
short half life opiod
metoclopramide (reglan)
antiemetic increases gastric motility
Meperidine
anticonvulsive
Dantrolene
controls muscle spasm and malignant hyperthermia
decreases intracellular Ca
Potency is
increased with lipid solubility
onset is
decreased by pKA