Endocrine

Question 1

Papillary thyroid cancer

Answer 1

Most common, differentiated and slow growing. Can be treated by surgery or radioablation

Question 2

Follicular thyroid cancer

Answer 2

Second most common, differentiated, Can be treated by surgery or radioablation

Question 3

Medullary cancer

Answer 3

Sometimes can be familial and associated with other endocrine malignancies.

Question 4

Lymphoma of thyroid

Answer 4

Non-Hodgkin’s B cell lymphoma, may occur in ong standing hashimoto’s thyroiditis. Rapidly expanding mass with lymphadenopathy, can be cured

Question 5

Anaplastic thyroid cancer

Answer 5

Rapidly expanding mass, poor prognosis.

Question 6

Reidel’s thyroiditis

Answer 6

Rare, chronic inflammatory disease of the thyroid gland characterized by a dense fibrosis that replaces normal thyroid parenchyma. Associated with sclerosing cholangitis, mediastinal/retroperitoneal fibrosis.

Question 7

Grave’s disease

Answer 7

Autoimmune disease causing thyrotoxicosis. Features: pretibial myxedema, exophalmos, lid lag, signs of thyrotoxicosis,

Question 8

Hashimoto’s disease

Answer 8

Autoimmune disease in which the thyroid gland is gradually destroyed. Enlarging painless goitre.

Question 9

de Quervain’s thyroiditis (subacute thyroiditis)

Answer 9

Painful thyroid with thytotoxicosis. Causes: postpartum, viral URTI

Question 10

Toxic multinodular goiter

Answer 10

Second most common cause of hyperthyroidism.