Endocrine Flashcards

1
Q

Which insulin do you give once a day?

A

basal (long acting) eg lantus

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2
Q

Which diabetic drug is weight neutral?

A

DPP4 inhibitors eg sitagliptin

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3
Q

What is strawberry milkshake coloured blood?

A

hyperlipidaemia

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4
Q

What are the calcium, phosphate and alkaline phosphate levels in Paget’s disease?

A

normal calcium and phosphate, high alkaline phosphate

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5
Q

Which hormone tests for pregnancy?

A

HCG

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6
Q

Which hormone peaks before ovulation?

A

LH (about 12 hrs before)

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7
Q

Which hormone is used to test for fertility?

A

progesterone

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8
Q

Which is Paget’s?

A

increased osteoclastic reabsorption followed by increased osteoblastic activity

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9
Q

Key words for Paget’s?

A

family history, male, old age, FH, bone pain (pelvis, lumbar spine, femur)

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10
Q

What is Pagets linked to?

A

deafness, cardiac failure, fractures, skull thickening

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11
Q

What is osteomalacia in children?

A

rickets

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12
Q

What are the calcium, phosphate and alk, phosphate levels in osteomalacia?

A

low calcium and phosphate

high alk,phosphate

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13
Q

What happens to bone in osteomalacia?

A

abnormal softening of bone due to mineralization of osteoid (immature) bone

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14
Q

Causes of osteomalacia?

A

malabsorption, poor diet or lack of sunlight

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15
Q

Symptoms/signs of osteomalacia?

A

bone pain, tenderness, fractures (especially femoral neck), proximal myopathy, waddling gait

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16
Q

Treatment of Paget’s?

A

bisphosphonate (risedronate)

17
Q

Treatment of osteomalacia?

A

vit D therapy

with calcium and phosphate supplements

18
Q

Key words - bony metastases..?

A

high calcium
osteoclast formation
bone pain