Endocrine-2 (Topical Steroids)

Question 1

What is the mechanism of action in topical corticosteroids?

Answer 1

Binds to steroid receptor complex in cytoplasm of skin cells
- Anti-inflammatory
- Immunosuppressive
- Anti-proliferative

Question 2

What is a “general rule” of topical corticosteroids?

Answer 2

Ointments and gels are more potent than creams and lotions

Question 3

What enhances the absorption of topical corticosteroids?

Answer 3

Skin hydration, occlusive dressings

Question 4

What are lower potency agents are effective for what?

Answer 4

Treating acute, inflammatory skin

Question 5

What are some adverse effects of topical corticosteroids?

Answer 5

• Atrophy
• Abnormal dilation of blood vessels (telangiectasia)
• Visible linear scars (striae)

Question 6

How often are topical corticosteroids usually applied?

Answer 6

1-2x daily

Question 7

How much of a topical corticosteroid should be applied?

Answer 7

1 “fingertip unit”
(tip of finger to first index)