Endocrine-2 (Parathyroid Gland/Calcium Homeostasis/Vit D) Flashcards
Does an increase of PTH increase or decrease calcium levels?
Increase
What are some disorders of the parathyroid gland?
- Primary hypoparathyroidism
- Primary hyperparathyroidism
- Secondary hypoparathyroidism
- Secondary hyperparathyroidism
Vitamin D2
Ergocalciferol
Vitamin D3
Cholecalciferol
Are vitamins D2 and D3 physiologically active or inactive?
Inactive
25(OH) D
Calcidol
What is calcidol?
Storage form of vitamin D, used to monitor drug therapy
1,25(OH)2 D
Calcitriol
What is calcitriol?
Physiologically active form of vitamin D
What is the primary site of action of calcitonin?
Bone
What is the mechanism of action of calcitonin?
Potent inhibitor of osteoclasts
What dosage form is calcitonin available in?
Nasal spray 200units/spray
What does a vitamin D deficiency result in?
Hypocalcemia
What are some examples of vitamin D replacement therapy?
- Drisdol 50,000 IU/cap
- Rocaltrol 0.25/0.5mcg capsules (Calcitriol)