Endocrine Flashcards
Define and describe gross anatomy of the Endocrine system
Glands: Hypothalamus, pituitary gland, pineal gland, thyroid gland, parathyroid gland, thymus, adrenal glands.
Organs: Pancreas, kidneys, ovaries, testes
Endocrine vs. Nervous System
Compare the control of mediator molecules
NS: Neurotransmitters released locally in response to nerve impulses
ES: Hormones delivered to tissues throughout the body by blood
Endocrine vs. Nervous System
Compare the site of mediator action
NS: Close to site of release, at a synapse; binds to receptors in postsynaptic membrane.
ES: Far from site of release (usually); binds to receptors on or in target cells.
Endocrine vs. Nervous System
Compare the types of target cells
NS: Muscles,
gland cells, other neurons.
ES: Cells throughout the body.
Endocrine vs. Nervous System
Compare the time to onset of action
NS: Typically within milliseconds (thousands of a second).
ES: Seconds to hours or days.
Endocrine vs. Nervous System
Compare the duration of action
NS: Generally short term (milliseconds)
ES: Generally longer (seconds to days)
Anterior Pituitary
Where are hypothalamic hormones released?
Into special blood vessels
Anterior Pituitary
What controls the release of hormones?
Hypophyseal portal system
Anterior Pituitary: Endocrine gland
What are the steps for hormone release?
- Hypothalamic neurons secrete releasing hormones into the primary capillary plexus
- The Hypothalamic hormones travel through portal veins to the AP where they stimulate release of hormones made in the AP.
- Rhe response of releasing hormones, the AP secretes hormones in the secondary capillary plexus. This then empties into the general circulation.
Posterior Pituitary: Nueroendocrine
Where do nerve impulses travel down?
The axons of hypothalamic nuerons
Posterior Pituitary: Nueroendocrine
Where are hormones released?
From their axon terminals in the posterior pituitary
Posterior Pituitary: Nueroendocrine
What are the steps for hormone release?
- Hypothalamic neurons synthesize oxytocin or antidiuretic hormone (ADH)
- Oxytocin and ADH are transported down the axons of the hypothalmohypophyseal tract to the posterior pituitary gland.
- Oxytocin and ADH are stored in neurosecretory bodies in the posterior pituitary.
- Nerve impulses arrive at neurosecretory bodies causing oxytocin or ADH to be released into blood.
Thyroid Gland
Describe structure of the gland
In the antieror neck and made up of follicular and parafollicular cells.
Thyroid Gland
What is the function?
Secretes thyroid hormone and calcitonin
Thyroid Gland
What are the function of the follicular cells?
Produce two thyroid hormones: T3 and T4