Endocrine Flashcards

1
Q

Drugs in the same category have similar what? (4)

A

adverse drug reactions
contraindications/precautions
administration considerations
therapeutic effects

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2
Q

Which drugs name is not capitalized?

A

generic drugs

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3
Q

what drugs are potentially harmful if there is no supervision from licensed health provider?

A

prescription

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4
Q

What are characteristics of OTC meds?

A

FDA says they are relatively safe to take w/o supervision
purchase anywhere by anyone

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5
Q

Pharmaceutics address what?

A

dissolution
absorption rate
onset of action

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6
Q

EC drugs can be abbreviated as what?

A

ER
XL
SR
XR

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7
Q

How can parenteral drugs be administered?

A

IV
subcut
IM

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8
Q

How does water-solubility affect drug absorption?

A

Absorption of drugs is rapid if drugs is highly-water soluble

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9
Q

What are the glands that make up the endocrine system?

A

hypothalamus
pituitary
thyroid/parathyroid
Islet cells
adrenal
testes/ovaries

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10
Q

What are five hormones that are stimulated in the anterior pituitary by the Hypothalamus?

A

GH
TSH
ACTH
FSH
LH

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11
Q

What two hormones does GnRH release in the anterior pituitary?

A

FSH and LH

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12
Q

What are two hormones that are stimulated in the posterior pituitary by the Hypothalamus?

A

antidiuretic
oxytocin

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13
Q

What chemical is needed to produce T3 and T4?

A

iodine

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14
Q

What chemical are T4 and T3?

A

thyroxine
triiodothyronine

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15
Q

Cells in the Islets of Langerhans produce what?

A

beta cells produce insulin and amylin

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16
Q

What are some negative effects of glucose in the ciculatory system?

A

CV Kidney disease
HD
CVA

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17
Q

What hormone balances the effects of insulin and three other effects?

A

slows gastric emptying
inhibits secretion of glucagon
enhances feeling of satiety

18
Q

What type of patients are prone to insulin resistance?

A

overweight or obese

19
Q

What does the adrenal cortex produce?

A

corticosteroid hormones:
cortisol
aldosterone
androgen
estrogen

20
Q

What hormone does the adrenal medulla produce?

A

SNS stimulation
epinephrine
norepinephrine

21
Q

What are six types of oral hypoglycemics?

A

sulfonylureas
meglitinides
biguanides
thiazolidinediones
alpha-glucosidase inhibitor
gliptins

22
Q

What classification of oral antidiabetic drugs decrease the reabsorption of glucose?

A

sodium-glucose co-transperter 2 (SCLT-2)

23
Q

What mechanism does sodium-glucose co-transperter 2 (SCLT-2) use to treat diabetes symptoms?

A

increases excretion of glucose in urine
improved glycemic control
weight loss

24
Q

What is the prototype drug for thyroid replacement therapy?

A

Levothyroxine aka Synthroid

25
Q

Antithyroid drugs are used for what condition?

A

Graves disease to supprose thyroid hormone

26
Q

What is the prototype drug for antithyroid drug?

A

propylthiouracil

27
Q

What is the lack of growth hormone called?

A

Turner’s syndrom, usually affecting girls to reach a normal height

28
Q

What is the prototype drug for growth hormone?

A

somatropin
genotropin
nutropin
humatrope
serostim

29
Q

What does a vasopressin do?

A

it decreases water extretion by the kidneys by increasing water reabsorption in the collecting ducts
another effect is constricting aterioles in the body

30
Q

What do glucocorticoids do for the body?

A

replaces cortisol from diseases such as Addison’s disease

31
Q

What does cortisol do to the body? (2)

A

promotes breakdown of proteins and lipids to synthesize more glucose
increases with stress to ensure blood pressure and adequate blood glucose levels

32
Q

What do mineralocorticoids treat??

A

hypoaldosteronism
congenital adrenal hyperplasia
Addison’s disease

33
Q

Why should thyroid repacements be taken on an empty stomach?

A

they reduce the absorption of levothyroxine

34
Q

Why do people undergoing cancer treatment have be careful when taking radioactive iodine?

A

watch for tiredness, and slowness (hyperthyroidism)
and being around people, breastfeeding, etc

35
Q

What is the major adverse effect of growth hormone?

A

hyperglycemia, especially those with pre-existing diabetes

36
Q

What does Antidiuretic hormon treat?

A

diabetic insipidus

37
Q

What does diabetes insipidus due to the body?

A

produces anadequate amount of ADH and makes you pee too much

38
Q

What are some ADH drugs?

A

DDAVP
simate
minirin

39
Q

What are some adverse drug reactions to ADH?

A

hyponatremia, vasoconstriction with vasopression
seizures (b/c hyponatremic)

40
Q

Why should hydrocortisone be given with meals?

A

decrease GI upset and mimic normal cortisol secretions in the morning and adjusted dose in the evening

41
Q

What kind of diet should people be on with glucocorticoid therapy?

A

high protein, calcium and potassium
lower sodium and carbs

42
Q

Metformin is contraindicated for what?

A

contrast procedures