ENDOCRIN Flashcards

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1
Q

glande endocrine

A

hipofiza epifiza tiroida paratiroida timus suprarenala pancreas ovar testicul
temporar placenta

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2
Q

alte organe cu rol endocrin

A

antru piloric duodenul rinichii cordul adipocitele + unii neuroni hipotalamici

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3
Q

h antru piloric

A

gastrina

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4
Q

efecte gastrina

A

controleaza forta contract peristaltice gastrice
+ secretia HCl

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5
Q

h duoden

A

6-8 hormoni
colecistokinina
secretina

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6
Q

efect secretina

A

+ secretia HCl

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7
Q

efecte colecistokinina

A

+ secretia biliara

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8
Q

h rinichi

A

renina + eritropoietina

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9
Q

h sist mientric

A

somatostatina GH-IH

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10
Q

rol somatostatina

A
  • secretia HCl
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11
Q

h hipotalamus ant

A

vasopresina/antidiuretic/ADH
ocitocina/oxitocina

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12
Q

h hipotal mijlociu

A

somatostatina CRH TRH GRH h de inhibare a secretiei de MSH

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13
Q

diametru hipofiza

A

1.3 cm

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14
Q

greutate hipofiza

A

500 mg

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15
Q

localizare hipofiza

A

baza craniului post de chiasma
pe saua turceasca a sfenoidului

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16
Q

lobi hipofiza

A

anterior 75/100
mijlociu 2/100 - simpla lama epiteliala
posterior 23/100

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17
Q

ncl mij hipotal - adenohipofiza

A

tija pituitara = sist port hipotalamo-hipofizar

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18
Q

ncl ant hipotal - neurohipofiza

A

tract nervos hipotalamo-hipofizar

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19
Q

h glandulotropi

A

ACTH TSH FSH LH

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20
Q

h non-glandulotropi

A

STH LTH

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21
Q

h crestere

A

STH T3 T4 INSULINA GONADICI

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22
Q

efecte STH

A

condrogeneza
ingrosare oase lungi + dezvoltare oase late
crestere muschi + viscere
retentie de Ca Na K P N

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23
Q

efecte metabolice STH

A

proteic anabolism
glucidic catabolism + GNG -GLICOLIZA
lipidic catabolism

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24
Q

hipersecretie STH copil

A

gigantism

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25
Q

hipersecretie STH adult

A

acromegalie

26
Q

hiposecretia STH copil

A

nanism hipofizar

27
Q

hiposecretia STH adult

A

casexia hipofizara

28
Q

nume prolactina

A

LTH luteotrop

29
Q

efecte LTH

A

+ secretia lactata
previne ovulatia
inhibator gonadotrop
favoriz excretia laptelui
+ secretia de estrogeni si progesteron a corpului galben

30
Q

stim secretie lactata

A

in sarcina suptul
in afara sarcinii efortul stresul somnul hipoglicemia

31
Q

inhiba secretia de lapte

A

estrogenii si progesteronul

32
Q

ACTH adenocorticotrop efecte

A

+ activ secretorie CSR
creste c sangvina a glucocorticoizi + h sexosteroizi
stim direct melanogeneza

33
Q

hipersecretia ACTH

A

sindrom Cushing - diabet bronzat - exces glucocortic

34
Q

hiposecretia ACTH

A

boala adison - deficit glucocorticoizi

35
Q

lipsa ACTH

A

atrofia suprarenala

36
Q

tireotrop TSH tireostimulina

A

stim sinteza si secretia de h tiroidieni

37
Q

hiposecretie TSH

A

insuficienta tiroidiana - piele uscata, crestere greutate, vorbire lenta, dureri musc si artic

38
Q

hipersecretia TSH

A

basedow-graves - hipertrofie tiroida, hipersecretie T3, scadere greutate, crestere metabol bazal si frecv cardiaca, hipersudoratii

39
Q

h gonadotropi

A

FSH - foliculostimulant
LH - luteinizant

40
Q

efecte FSH barbat

A

+spermatogeneza +dezv tubi seminiferi

41
Q

efecte FSH femeie

A

cresterea si maturarea folic de graaf
+ secretia de estrogeni

42
Q

efecte LH barbat

A

+ secretia de androgeni, cel interstit testiculare Leydig

43
Q

efecte LH femeie

A

det ovulatia si aparitia corpului galben
+ secretia de estrogeni si progesteron

44
Q

MSH melanocitostimulant precursor

A

precursor comun cu ACTH

45
Q

MSH efecte

A

+pigmentogeneza
implicat in procesele de sinteza a rodopsinei

46
Q

oxitocina/ocitocina efecte

A

+ contractia musc netede a uterului gravid, canalelor galactofore, efectia laptelui

47
Q

antidiuretic/vasopresina/ADH efecte

A

creste absorbita facult. pe tubii distali+colectori
scade volumul si creste conc urinei
scade secretia gld exocrine
mentine v lichide org
vasoconstrictor in doze mari

48
Q

hiposecretie ADH

A

diabet insipid - poliurie polidipsie pierderi mari apa dezechilibre ionice

49
Q

suprarenale alc

A

corticala - periferie
medulara

50
Q

CSR tip hormoni

A

lipidici
din colesterol

51
Q

ex h CSR

A

aldosteron
cortizon cortizol
androgeni estrogeni

52
Q

mineralocorticoizi hormoni

A

aldosteron

53
Q

efecte aldosteron

A

metabol saruri minerale
reabsorbia Na+ in schimbul K+/H+ - excretati la niv tubi distali+colectori
se prod kaliurie si acidurie
retentie Na+ -> mentine pres osmotica a mediului intern/a vol sangv + eab

54
Q

origini embrionare CSR MSR

A

csr - mezoderm
msr - ectoderm

55
Q

cel tinta aldosteron

A

gld sudoripare salivare colice

56
Q

hipersecretie aldosteron

A

boala Conn - retentie sare si apa
edeme hipertensiune tulb metabol electrolitic

57
Q

hiposecretie aldosteron

A

boala Addison - pierdere sare si apa hipotensiune adinamie

58
Q

glucocorticoizii hormoni

A

cortizon hidrocortizon/cortizol - circula legati de prot plasmatice

59
Q

efecte glucocorticoizi sist osos

A

catabolism - diminueaza sinteza matricei organice + absorbtia intestinala a calciului

60
Q

efecte glucocorticoizi fc sup SNV

A

scadere cantit det - modif EEG alterare personalit modif senzoriale

61
Q

efecte glucocorticoizi org hematopoietice

A

scade nr EOZINOFILE BAZOFILE CIRCULANTE LIMFOCITE CIRCULANTE
creste stabiit membr lizozomale + nr NEUTROFILE PLACHETE HEMATII