Endocarditis Flashcards
What is endocarditis?
infection of heart valves and other heart tissue
Who often gets endocarditis?
> 50 and PWID
Explain briefly the pathophysiology of endocarditis?
trauma of heart= place to colonize OR thrombus- thrombus protects
What is considered acute endocarditis?
normal valves, often staph aureus, severe and rapid
What is considered subacute endocarditis
months, valve disease, hx of dental work, strep or entero
What is the time frame of prosthetic valve endocarditis?
in 1 year, usually stapoh
Risk factors for endocarditis?
male,>50, PWID, Heart disease, DM, bad oral hygiene
Which people generally get staph aureus endocarditis?
PWID
Which people get strep endocarditis?
from dental or resp surgery
Which people get enterocci endocarditis?
Gi surgery
Sx of endocarditis?
fever, heart murmer, fatigue, weight loss, osler nodes, janeway lesions, splinter hemorrhages, petechiae embolism
What is osler nodes?
purple painful nodes
What are janeway lesions?
red painless lesions on hands and feeet
What are splinter hemorrhages?
bleeding under nails
What are petechiae?
painless bleeding in eye bed
Which type of endocarditis (left or right) does IV drug use cause?
right= presents with lung sx
What do labs show for endocarditis?
increased WBC, NORMAL ANEMIA, ESRP, RF
How do you perform a proper blood sample?
from 3 different sites
For diagnosis, how many major and minor factors are definite endocarditis?
2 major or 1 major and 3 minor or 5 minor
What can happen if endocarditis is not treated?
destruction of valve, HF, stroke
Why are bacteria hard to kill in endocarditis?
vegetation protect
in dense area so b lactamase high amounts
How long is typical therapy for endocarditis?
4-6 weeks
What is empiric therapy for endocarditis?
Pen G/ amp and AMG
What clues indicate staph aureus?
Iv Drug user, skin disorder, burns, AIDS, DM
