endo part 2 Flashcards

1
Q

all types of insulin are in?

A

the fridge

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2
Q

rapid acting insulin examples?

A

lispro, aspart (novolog)

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3
Q

when should u take rapid acting insulin?

A

before meals

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4
Q

how do u administer regular insulin?

A

IV or SQ

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5
Q

duration of rapid insulin?

A

10-30 mins, peak: 30- mins to 3hrs, (duration: 3-5hr)

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6
Q

regular insulin is?

A

short acting (3-4 hrs)

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7
Q

examples of regular insulin?

A

humlin R and novolin R

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8
Q

what is the duration for short acting insulin?

A

onset: 30-1hr–>peak: 2-5 hrs–> (duration: 5-8 hrs)

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9
Q

what are some examples of intermediate-acting insulin

A

NPH (appearance is cloudy)

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10
Q

what is the duration for intermediate insulins?

A

onset: 1.5-4hrs–> peak: 4-12 hrs–> (duration: 12-18 hrs)

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11
Q

which insulin is sliding scale only?

A

short acting (regular)

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12
Q

long acting insulin is for?

A

24 hr use

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13
Q

what can you NOT do with long acting insulin?

A

can’t mix other insulins together (must be two different shots

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14
Q

what is the medication for inhaled insulin?

A

afrezza

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15
Q

what is the starter medication for diabetes?

A

metformin (for insulin)

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16
Q

only insulin that is IV?

A

regular

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17
Q

what is duration of NPH?

A

8 hrs

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18
Q

when should stop the metformin?

A

when they want to do test on kidneys; requires dye injection (48 hours before and after test)

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19
Q

what happens when you dont stop the metformin for test?

A

build up of lactic acid

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20
Q

example of insulin that lasts A LONG time?

A

lantus (glargine)

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21
Q

how does lantis work?

A

inject crystal and melts within 24 hrs

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22
Q

what medication lands on beta cells and tells them “make more insulin”

A

Glipizide (sulfonylureas/Secretagogue )

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23
Q

Secretagogue is?

A

substance that stimulates the secretion of another substance.

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24
Q

what is Canagliflozin ?

A

oral diabetes medication -is GLT2 inhibitors
(Sodium-Glucose Co-Transporter 2 inhibitors)

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25
what are GLT2 inhibitors (Sodium-Glucose Co-Transporter 2 inhibitors)?
switches na+ in urine to glucose in urine (lower blood sugar levels) -longer duration of action (24hr)
26
what is a risk of GLT2 inhibitors
UTI
27
prandin is?
for diabetes (short duration of action but works FAST) -nonsulfonylurea Secretagogue
28
if a pateint has hypoglycemia, what medication should u give?
glucagon
29
what does glucagon do?
increases blood sugar and breakdown glycogen
30
what is stored in the liver?
glycogen
31
glycogen turns into?
glucose
32
you are preggy with diabetes, what medication do u give?
insulin (can't give PO meds)
33
prandial (pre-before, post-after)
during meal
34
glipizide is?
makes more insulin PO -sulfonylureas
35
sulfonylureas do what?
stimulate beta cells of liver to= MAKE MORE INSULIN
36
prednisone is?
glucocorticoids, increase blood sugar levels. -caused GI issues (take with food/dariy)
37
glucocorticoids released by
adrenal cortex
38
when you stop prednisone how should u stop it?
TAPER down, ween it off, bit by bit, and lead to reserve action (asthma or inflammation)--> leads to HIGH BP
39
what are the signs and symptoms that pt is taking too much Synthroid (thyroid hormone) med?
bugging eyes, thyroid swollen, dry skin
40
what is synthroid made out of?
t4 (RAISE metabolism)
41
what surrounds synthroid?
iodine
42
what is stronger? t3 or t4?
t3
43
if body needs higher metabolism, what happens?
t4 becomes t3 (in tissues)
44
If TSH is high
means too little thyroid (increase dosage)
45
if TSH is down
means too high or normal (lower thyroid med)
46
TSH comes from
anterior pituary gland
47
hyperthyroid
thyroid doesn't work= TSH level low (high T3/T4 thyroid level)
48
hypothyroid
TSH high= (thyroid T3 and T4 level low)
49
glucocorticoids makes immune system go?
down (more are made in time of stress)
50
glucocorticoids increase?
glucose levels (controls carbs, protein, fat) metabolism
51
what is the word that blood glucose levels are normal?
euglycemia
52
what is the big carb molecule (polysaccharide) in liver?
glycogen
53
gland where the t cells go?
Thymus
54
name of hormone that thyroid releases that makes blood calcium go down?
calcitonin
55
very thirsty when u have diabetes
polydipsia
56
glycogenolysis
break down glycogen (in liver) to make glucose
57
glucagon lands on liver to do?
tell it to break down glycogen
58
Glycogenesis
glucose to glycogen.
59
what medication treats graves disease?
PTU (propylthiouracil)
60