endo drug sea Flashcards

1
Q

acarbose (alpha-glucosidase inhibitor)

A

GI disturbances

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2
Q

Metformin (biguanide)

A

GI upset, lactic acidosis (contraindicated in renal failure)

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3
Q

canagliflozin (SGLT-2 inhibitor)

A

glucosuria, UTI, vaginal yeast infections

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4
Q

cinacalcet

A

hypocalcemia

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5
Q

glimepiride (2nd gen sulfoylurea)

A

hypoglycemia

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6
Q

glipizide (2nd gen sulfoylurea)

A

hypoglycemia

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7
Q

glyburide (2nd gen sulfoylurea)

A

hypoglycemia

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8
Q

pramlintide (amylin analogs)

A

hypoglycemia, nausea, diarrhea

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9
Q

glucocorticoids

A

iatrogenic cushings (hypertenision, weight gain, moon facies, buffalo hump, striae, osteoporosis, hyperglycemia, amenorrhea, immunosuppression), steroid diabetes, steroid psychosis

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10
Q

chlorpropamide (1st gen sulfonylurea)

A

increased risk of hypoglycemia in renal failure, disulfiram-like effects

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11
Q

tolbutamide (1st gen sulfonylurea)

A

increased risk of hypoglycemia in renal failure, disulfiram-like effects

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12
Q

linagliptin (DPP-4 inhibitor)

A

mild urinary or respiratory infections

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13
Q

saxagliptin (DPP-4 inhibitor)

A

mild urinary or respiratory infections

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14
Q

sitagliptin (DPP-4 inhibitor)

A

mild urinary or respiratory infections

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15
Q

exenatide (GLP-1 analog)

A

nausea, vomiting, pancreatitis

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16
Q

liraglutide (GLP-1 analog)

A

nausea, vomiting, pancreatitis

17
Q

demeclocycline

A

nephrogenic DI, photosensitivity, abnormalities of bone and teeth

18
Q

propylthiouracil

A

skin rash, agranulocytosis (Rare), aplastic anemia, hepatotoxcity

19
Q

methimazole

A

skin rash, agranulocytosis (Rare), aplastic anemia, possible teratogen (aplasia cutis)

20
Q

pioglitazone, rosiglitazone (glitazones, thiazolidinediones)

A

weight gain, edema, hepatotoxicity, heart failure, increased risk of fractures