endo drug sea Flashcards
acarbose (alpha-glucosidase inhibitor)
GI disturbances
Metformin (biguanide)
GI upset, lactic acidosis (contraindicated in renal failure)
canagliflozin (SGLT-2 inhibitor)
glucosuria, UTI, vaginal yeast infections
cinacalcet
hypocalcemia
glimepiride (2nd gen sulfoylurea)
hypoglycemia
glipizide (2nd gen sulfoylurea)
hypoglycemia
glyburide (2nd gen sulfoylurea)
hypoglycemia
pramlintide (amylin analogs)
hypoglycemia, nausea, diarrhea
glucocorticoids
iatrogenic cushings (hypertenision, weight gain, moon facies, buffalo hump, striae, osteoporosis, hyperglycemia, amenorrhea, immunosuppression), steroid diabetes, steroid psychosis
chlorpropamide (1st gen sulfonylurea)
increased risk of hypoglycemia in renal failure, disulfiram-like effects
tolbutamide (1st gen sulfonylurea)
increased risk of hypoglycemia in renal failure, disulfiram-like effects
linagliptin (DPP-4 inhibitor)
mild urinary or respiratory infections
saxagliptin (DPP-4 inhibitor)
mild urinary or respiratory infections
sitagliptin (DPP-4 inhibitor)
mild urinary or respiratory infections
exenatide (GLP-1 analog)
nausea, vomiting, pancreatitis