adrenergic meds Flashcards
bethanechol
activates bowel/bladder smooth muscle; resistant to acetylcholinesterase
pilocarpine
contracts ciliary muscle of the eye (open angle glaucoma); contracts pupillary sphincter (closed angle glaucoma); resistant to acetylcholinesterase
dopamine
D1=D2>>
scombroid poisoning
improperly stored dark-meat fish–> bacterial histidine decarboxylase convertes histidine to histamine (which causes the allergy like symptoms)
donepezil
increases ACh
galantamine
increases ACh
rivastigmine
increases ACh
edrophonium
increases ACh
pyridostigmine
increases ACh, increases muscle strength; does not penetrate CNS
physostigmine
increases ACh, penetrates CNS
neostigmine
increases ACh; no CNS penetration
ephedrine
indirect general agonist, releases stored catecholamines
cocaine
indirect general agonist, reuptake inhibitor
amphetamine
indirect general agonist, reuptake inhibitor, releases stored catecholamines
phenoxybenzamine
irreversible non-selective alpha blockade
carvedilol
non-selective alpha and beta antagonists (so is labetalol)
timolol
non-selective beta antagonist _1=_2
ciguatoxin
opens Na+ channels causing depolarization
phentolamine
reversible non-selective alpha blockade
methacholine
stimulates muscarinic receptors in airway when inhaled, causes bronchoconstriction
tetrodotoxin
toxin binds fast voltage-gated Na+ channels in cardiac and nerve tissue preventing depolarization (blocks AP)
prazosin
_1-selective blocker
terazosin
_1-selective blocker
doxazosin
_1-selective blocker
