endo Flashcards
MC cause of hypothyroidism?
Hashimoto Thyroiditis
TSH level in Hasimoto Thyroiditis?
elevated TSH
Which 2 antibodies positive in Hashimoto Thyroiditis?
positive anti-thyroid peroxidase antibodies
positive anti-thyroglobulin antibodies
T4 level in Hashimoto Thyroiditis?
low T4
Test for Diabetes Insipidus?
Desmopressin stimulation test
Sodium levels in DI?
Hypernatremia
DKA fluid deficit about how much?
5-10L (100mL/kg)
Best IVF for DKA?
NS
Rate of insulin infusion for DKA?
0.1U/kg/hr
When to change fluid during treatment for DKA?
When BGL at 200.
When BGL at 200 in DKA what to change fluid to? To prevent what?
Change to 5% Dextrose in 0.45% Saline and reduce insulin infusion. To avoid iatrogenic hypoglycemia and cerebral edema.
When to stop insulin infusion in DKA? (2 things)
Ketonemia clears and anion gap normalized
How much does sodium level decrease by for every 100 glucose above 100?
1.6 (140 at 100 to 138.4 at 200)
PTH deficiency does what to calcium levels?
Hypocalcemia
Hypocalcemia does what to muscles?
Neuromuscular irritability, increased DTRs, Trousseau carpal pedal spasm and Chovstek’s facial contractionsign
Hypocalcemia on EKG?
Prolonged QT interval
Low PTH does what to Phosphorus?
High P
Free T4 level in hypothyroidism?
Low!
TSH levels in hypothyroidism?
High!
Define thyrotoxicosis
Excessive thyroid hormone concentration
Thyroid storm is an extreme manifestation of what?
thyrotoxicosis
What predominently causes thyroid storm?
Grave’s dz
Euthyroid sick syndrome happens when?
Abnormal thyroid tests when someone is sick and usually has normal thyroid
When does Euthyroid sick syndrome get better?
after recover from underlying illness
MC metabolic problem in neonates?
Hypoglycemia
Tx for neonate hypoglycemia?
5mL/kg of 10% Dextrose (aka D10)
Primary Adrenal Insufficiency aka
Addison Disease
Addison Disease skin and mucuous membranes?
Hyperpigmented skin and mucus membranes
Hyperpigmentation in Addisson’s Dz due to what?
Increased ACTH
Na and K in Addison Disease?
Hyponatremia
Hyperkalemia
Addison Disease due to low levels of which hormone?
Cortisol