Endo Flashcards

1
Q
Thyroid Gland produces 3 hormones
T3
-what is the synthetic version?
T4
-what is the synthetic version?
Calcitonin

Dietary Iodine is needed to make
Thyroid hormones gives us?

A

Triiodothyronine, more potent
- Liothyronine

Thyroxine
-Levothyroxine

Calcitonin decreases calcium by taking calcium out of the blood and pushing it back into the bone

Hormones
Energy

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2
Q

Hyperthyroidism

Nervous and Irritable
Attention Span
Appetite and weight
Sweaty/Hot
GI
Bp and pulse
Thyroid size is
Arryhthmia/palpitations
Exophthalmos
A

Produces too much energy. Aka Grave’s disease

Nervous because they have increased tachycardia and they are Irritable
Attention Span is decreased because they cant focus much
Increased Appetite but decreased weight due to increasee metabolism
Sweaty because they have increased energy and they have intolerance to heat
In GI they have diarrhea, increased bowel sounds because they have too much energy
Bp and pulse are increased
Increased
Arrythmia / palpitations is present in Hyperthyroidism, that is why thyroid storm is an emergency
Exophthalmos is bulging eyes

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3
Q

Diagnosis of Hyperthyroid

T4 is
TSH is
Thyroid scan is
-1 week prior and 6 weeks

Ultrasounds,CT,MRI

A

T4 is increased but TSH is decreased
The thyroid scan is BIG and GLOWING
- must discontinue any iodine containing meds and must wait 6 weeks to restart meds

These are more commonly used

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4
Q

Amiodarone

A

Is an antiarrhythmic drug, that contains high level of iodine

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5
Q

Treatment for Graves

Anti-thyroids(methimazole,propylthiouracil)

  • stops the
  • Pre Op
  • euthyroid

Iodine compounds: POTASSIUM IODINE, like

  • vascularity and size
  • stains teeth

Betablockers

  • Myocardial contractility
  • BP and HR
  • Anxiety
  • asthmatic or diabetics
  • epi and norepi
A

They Stop thyroid from making thyroid hormone
It is used Pre-op to stun the thyroid
Goal is to become Euthyroid( normal )

SSKI and Lugol’s Solution
Vascularity and Size of the thyroid gland is decreased. All endocrine Glands are very Vascular
It must be given with milk or juice and use a straw because ot stains teeth

Betablockers decreases myocardial contractility . Which decreases BP and HR
Anxiety is decreased when taking beta blockers
DONT give to patients with asthma or diabetics they could precipitate an attack
Beta blockers dont release epi and norepi

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6
Q

Treatment for Graves

Radioactive iodine therapy

  • dose
  • route
  • pregnancy
  • destroys
  • radioactive precautions
  • rebound effect is
A

One dose is needed and is given PO (either liquid or tablet form)
Must rule out pregnancy first
It destroys thyroid cells, hypothyroidism is expected
Stay away from babies for 1 week and dont kiss anyone for 1 week. Must think: Unsealed Radiation
The rebound effect of radioactive therapy is Thyroid Storm, this is an emergency situation could lead to heart attack.

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7
Q

Thyroidectomy (partial/complete)

Post op:
Priority is
Must report
Where to check for bleeding?

Assess for recurrent laryngeal nerve damage by listening for
Paralysis of vocal cords

Could lead to hypocalcemia

Support neck
Personal items
Position
Nutrition

A

Priority is hemorrhage.
Must report feelings of pressure on neck
Behind the neck and Incision site

Hoarseness and weak voice
Paralysis of vocal cords could lead to airway obstruction, immediate trach is needed

Could lead to hypocalcemia due to accidentally removing the parathyroid

Must be taught how to support the neck using pillows
Personal items must be put close to them to avoid stretching
HOB elevated to decrease edema
Nutrition client needs more calories pre and post

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8
Q

Hypothyroidism is

S/S:

No energy
Fatigue
No expression
Speech is
Weight and GI
Hot or Cold?
Treatment:
Synthetic t3 and t4
Taken on a
Take meds forever?
BP and HR
A

Decreased in T4 and Increased in TSH. Aka MYXEDEMA

If hyperthyroidism is too much energy, hypothyroidism has no energy because thyroid gives us Energy
The client is fatigue due to low energy
They dont have energy to even move face
Speech is Slow
Weight is increased because GI is Slow or decreased metabolism leading to constipation
They are cold intolerance, but must NOT pick a ☆☆HEATING PAD

T3 - liothyronine ( cytomel) and t4 - levothyroxine (synthroid)
Taken on a empty stomach
Yes, they take these meds lifetime
If they take these meds their BP and HR will increase because energy levels go UP

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9
Q

Hypothyroidism is same as S/S of

Hyperthyroidism is same as S/S of

A

Depression

Manic

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10
Q

PTH or Parathormone

Hyperparathyroidism
-client is

Hypoparathyroidism

  • client is
  • treatment
A

Pulls calcium from the bone and puts it in the blood. Increases serum calcium

Hyperparathyroidism is too much PTH, hypercalcemia, hypophosphatemia
- client is sedated

Hypoparathyroidism is not enough PTH, hypocalcemia, hyperphosphatemia

  • client is not sedated
  • phosphate binding drugs
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11
Q

Adrenal glands is needed for

2 parts are

A

STRESS

Adrenal cortex and Adrenal Medulla

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12
Q

Adrenal Medulla contains

Pheochromocytoma

S/S:
Bp and HR
Palpitations
Flushing or
Headache?

It is diagnosed by

  • epi norepi
  • VMA and MN(24 hour urine)

Foods that alter VMA and MN
“ BBVaCaF “

Treatment:

A

Epinephrine and Norepinephrine. Epinephrine stimulates HR and Norepinephrine controls or maintains blood pressure

In pheochromocytoma, benign tumors are present which secretes epi and norepi in boluses. They tend to be familial so screen the family

Bp and HR are increased
Which leads to palpitations
Extremely diaphoretic
Yes. Headache will be experienced by these clients

Diagnosed by giving epi or norepi
Also diagnosed by checking cathecholamine levels using:
Vanillymandelic acid test
Metanephrine test
- this is screenes by 24 hour urine specimen, first void thrown away and keep last void

Anything with vanilla in it. Must not eat several days to a week
Banana
B vitamin
Vanilla
Caffeine
Fruit juices

Treatment is SURGERY to remove tumors

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13
Q

Palpating abdomen in Pheochromocytoma

A

AVOID!! Because it might cause sudden release of cathecholamines which will lead to severe Hypertension

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14
Q

Adrenal cortex contains

“Glucocorticoids regulate CALBI”

Mineralocorticoids aka

Sex hormones( testosterone, estrogen and progesterone)
Too many sex hormones
Not enough sex hormones

A

Glucocorticoids, mineralocorticoids and sex hormones– STEROIDS

Change your mood: depressed,psychotic,euphoric
Altered defense Mechanism, high risk for infection
Breakdown of Fats and Proteins
Inhibits insulin, leading to hyperglycemic

Aldosterone. Retains NA and H2O. Make you lose K

Too many sex hormones:
Horsutism
Acne
Irregular menstrual cycle

Not enough sex hormones:
Decreased axillary or pubic hair
Decreased libido

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15
Q

ACTH ( adrenocorticotropin hormones ) mase in pituitary and stimulates

Increased ACTH =

Just another fancy word. Think

A

Cortisol to be made. Cortisol is a hormone in adrenal cortex. Helps reduce inlfammation

Increased cortisol

Steroids.

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16
Q

Addisons is

S/S:
Vitiligo
Hyperpigmentation
NA,K,glucose
Extreme fatigue
Nausea vomiting and diarrhea
Anorexia/weight loss

Treatment:
Combat shock
Daily weight
Fluid volume

A

Decreased in steroids ( glucocorticoids, mineralocorticoids and sex hormones )

Vitiligo or white patchy area of depigmented skin
Bronzing color of the skin and mucous membranes
Decreased sodium, increased potassium,Hypoglycemia

Treat:
Increase sodium because they losing NA and H2O
Daily weight and I and O
Deficit, they are losing weight

17
Q

Meds for addisons disease

Prednisolone ( Prednisone )

  • given how many times a day?
  • 2/3 and 1/3

Fludrocortisone acetate

A

2x a day in split doses.
2/3 in morning and 1/3 in evening, this is how our body excrete glucocorticoid during the day

Fludrocortisone acetate is a Synthetic aldosterone

18
Q

When administering meds where weight needs to be monitored daily:

Must keep weight within

Report a gain of

Addisonian Crisis is

A

2 - 3 lbs or (1 to 2 kgs ) plus or minus their normal weight

A gain of >5 lbs per week

Severe Hypotension and Vascular Collapse. Same with addisons disease but 100x worse. Usually occurs due to stress, infections or stopping steroids abruptly

19
Q

What electrolyte will steroids decrease?

Long term use leads to?

Must avoid exposure to infection.why?

A

Calcium. They decrease it by excreting it through the GI tract.

Osteoporosis and Brittle Bones

Because they are also immunocompromised

20
Q

Cushings

Glucocorticoids:
Moon faced
Truncal obesity 
Buffalo hump
Lipolysis
A

Too many steroids

Moon faced, Truncal obesity and buffalo hump happens because of Fat redistribution, due to increased breakdown of Fats and Proteins, another possible reason is fluid volume excess
Lipolysis