ENDO Flashcards

1
Q

TTO DM TIPO 2 + I.H/I.R.C

A

INSULINA

Los ADO están contraindicados

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2
Q

TTO HIPERGLUCEMIAS AGUDAS O DESCOMPENSACION DM HOSPITALIZADOS

A

INSULINA

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3
Q

DIFERENCIA ENTRE insulina BIOSINTETICA Y ANALOGOS INSULINA

A

biosintetica: disminuyen Hb1Ac
Analogosos: no disminuyen Hb1Ac

Ambos disminuyen hipoglucemia nocturnas

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4
Q

Degludec

A

Ha demostrado disminuir hipoglucemias nocturnas mejor que glargina en Ensayos.

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5
Q

ETIOLOGIA DM 1

A

AI: Ac GAD+ y IA2+
Idiopatica: asiaticos/africanos

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6
Q

Heredabilidad DM1

A

Genetica + ambiental (infecciones parvovirus)
Hay impronta sexual (mayor riesgo los varones)
5-10% probabilidad en familiares primer grado

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7
Q

Heredabilidad DM2

A

POLIGENICA. Influencia genetica más importante que en DM tipo 1

40% probabilidad de heredar familiares

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8
Q

ADO que ha demostrado disminuir el riesgo CV en DM

A

Empagliflozina

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9
Q

HIPERCOLESTEROLEMIA FAMILIAR MONOGENICA HOMOCIGOTA

A

NIÑO ACV
COLESTEROL>500
XANTOMAS XANTOLESMAS

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10
Q

HIPERCOLESTEROLEMIA FAMILIAR MONOGENICA HETEROCIGOTA

A

COLESTEROL 300-500

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11
Q

HIPERCOLESTEROLEMIA POLIGENICA

A

COLESTEROL <300

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12
Q

QUÉ DAMOS CUANDO NO CONSEGUIMOS BAJAR COLESTEROL CON ESTATINAS

A

EVOLOCUMAB/ALIROCUMAB

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13
Q

QUE ES EVOLOCUMAB/ALIROCUMAB

A

Inhibidor de PCSK9, inhibe la degradación de LDL favoreciendo la captación de colesterol y disminuyendo sus niveles. Indicado cuando no se alcanza objetivo de LDL con estatinas.

Son los mas efectivos para disminuir el colesterol

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