endcrinology Flashcards

0
Q

Nateglinide and Repaglinide: side effects

A

Hypoglycemia

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1
Q

Contraindications to Thiazoladinediones

A

Patients with CHF should not take these drugs

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2
Q

In a patient with DKA, what is the most accurate way to measure the severity of the condition

A

Measure the serum bicarbonate level to determine the anion gap

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3
Q

treatment of Gastroparesis

A

Metoclopromide and erythromycin

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4
Q

diagnosis of gastroparesis

A

Gastric emptying study with tagged radioisotopes

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5
Q

treatment of diabetic retinopathy

A

laser photocoagulation

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6
Q

treatment of pain caused by diabetic neuropathy

A
Pregabalin
gabapentin
TCA(amytriptaline, nortryptaline)
duloxetine
carbamezapine
tramadol
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7
Q

mechanism of action of PTU

A

inhibits synthesis of new thyroid hormone in the thyroid glad

inhibits conversion of T4 to T3

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8
Q

Hyperthyroid drug that is safe to use in pregnancy

A

PTU

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9
Q

mechanism of action of methimazole

A

inhibits synthesis of new thyroid hormone in the thyroid glad

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10
Q

hyerthyroidism in a patient with recent study using IV contrast Iodine therapy

A

Jod-Basedow phenomenon

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11
Q

Lab findings associated with long term hypothyroidism

A

Hyperlipidemia
Hyponatremia
Elevated CPK

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12
Q

symptoms of hyperparathyroidism

A

stones: renal stones and nephrocalcinosis
Abdominal groans: constipation, peptic ulcers, N/V, pancreatitis
bones: osteitis fibrosa, osteoporois, osteomalacia, osteoarthritis
psychiatric overtones: depression, fatigue, lethargy, psychosis, AMS
Other: Proximl mm. weakness, itching, HTN, conjunctivitis, keratitis

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13
Q

when is surgery recommended in hyperparathyroidism

A
symptomatic patient
Ca++ >1.0 mg/dl above ULN
creatinine clearance reduced by 30%
BMD T-score: < -2.5 at any site
Age <50
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14
Q

What medications should be avoided in hyperparathyridism

A

Hydrochlorothiazides and Lithium

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15
Q

What 2 phosphate binders are used in patient with renal disease

A

Calcium carbonate and calcium acetate

16
Q

in chronic renal disease what medications are used to suppress PTH secretion

A

Vitmine D analogue (calcitriol)

Cinacalcet

17
Q

side effect of calcium chloride

A

cantral venous necrosis

18
Q

drugs that cause dopamine synthesis therefore causing hyperprolactonemia

A
Phenothiazine (thioridazine, prochlorperazine, promethazine)
resperidone
haloperidol
methyldopa
verapamil
19
Q

Lab abnormality that warrants search for thyroid function test for possible hypothyroidism

A

Hyperlipidemia
HypOnatremia
Elevated CPK

20
Q

Skin condition associated with glucagonoma

A

Necrolytic migratory erythema (NME)

  • annular, erythematous dermatitis with blistering and erosions within the areas of the eruption.
  • location: perioral, penieal, perianal, genital, lower abdomen