EMQs Flashcards
What is hyperplasia?
Increased no. of cells
Hormonally driven
What is hypertrophy?
Increased size of cells
No increase in number of cells
Due to increased workload
What is dysplasia?
Abnormal growth
Usually failure of normal maturation of epithelium, with partial expression of a neoplastic phenotype
Premalignant condition
What is Schirmer’s test?
Measures rate at which strip of filter paper suspended from lower eyelid is wetted by tears
Reduced tear production - keratoconjunctivitis sicca - one of the features of Sjogren’s syndrome - causes ocular discomfort and erosion
What is Hypromellose?
Artificial tears
Tx for keratoconjunctivitis sicca
Feature of Sjogren’s
What is initial treatment for chronic simple (open-angle) glaucoma?
Topical B blocker erg timolol
Significant systemic absorption can occur
Usual cautions and CIs to B blockers should be observed
What treatment can be used if a topical B blocker doesn’t reduce IOP sufficiently in chronic simple glaucoma?
Parasympathomimetics - pilocarpine
Selective a2 adrenoceptor agonists - brimonidine
Carbonic anhydrase inhibitors - dorzolamide
Prostaglandin analogues - latanoprost
What is antazoline?
Topical antihistamine
Tx for seasonal allergic conjunctivitis - hayfever
What is a commonly used short-acting mydriatic?
Tropicamide Aids fundoscopy Dilates pupil - max within 15 mins Effect wears off after 2h Can precipitate acute (closed-angle) glaucoma in elderly, long-sighted patients
What is atropine?
Long-acting mydriatic
Dilates pupil
What is fluroescein used for?
Aid to ocular examination
Highlights ocular injury
What causes a characteristic dendritic ulcer that can be visualised with fluorescein or rose bengal staining?
Herpes simplex keratitis Inflammation of cornea due to infection Pain Photophobia Impaired visual acuity, w localised corneal opacity
Treatment for bacterial conjunctivitis?
Topical chloramphenicol
But swabs for culture before tx started in case of resistance
What is Osler-Weber-Rendu disease?
Hereditary familial telangiectasia
Can give rise to severe and occasionally fatal haemorrhage
What is a pyogenic granuloma?
Raised, smooth swellings
Arise most frequently on Little’s area
Can cause severe bleeding - epistaxis
Can mimic a neoplasm